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[奈尤托莫林、奈尤胸腺素与2-氰基乙基脲的促白细胞生成作用比较]

[Comparison of the leukopoietic effect of NeyTumorin, NeyThymun and 2-cyanethyl-carbamide].

作者信息

von Ardenne M, Reitnauer P G

出版信息

Pharmazie. 1986 Apr;41(4):263-5.

PMID:3725871
Abstract

In an animal experiment (65 Wistar rats) NeyTumorin-Sol and NeyThymun-Sol f + k with 2-Cyanethyl-carbamide were examined in order to determine their leukopoietic and lymphopoietic effect respectively, which proved nearly equal and significant in all preparations. The maximum in the number of leukocytes with a medium elevation by a factor of 1.6 was found between the 14th and 25th day. The lymphopoiesis was especially stimulated with a medium elevation of the number of cells by a factor of 2.9. A repeated application didn't lead to an advantage compared with a single application. The combination of two different preparations resulted in the same or even worse findings compared with a separate administration of the various substances under examination.

摘要

在一项动物实验(65只Wistar大鼠)中,对NeyTumorin-Sol和NeyThymun-Sol f + k与2-氰乙基脲进行了检测,以分别确定它们的白细胞生成和淋巴细胞生成作用,结果证明在所有制剂中它们的作用几乎相同且显著。在第14天至25天之间发现白细胞数量最多增加了1.6倍。淋巴细胞生成受到特别刺激,细胞数量平均增加了2.9倍。与单次应用相比,重复应用没有优势。与单独施用各种受试物质相比,两种不同制剂的组合导致相同甚至更差的结果。

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