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揭开播散性鼻孢子虫病的神秘本质:复发性威胁的见解与挑战

Unveiling the Enigmatic Nature of Disseminated Rhinosporidiosis: Insights and Challenges of the recurrent menace.

作者信息

Kushwaha Akshat, Muralidaran Madhubala, Lakshmanan Jijitha, Raja Kalaiarasi

机构信息

Department of Otorhinolaryngology, JIPMER, Puducherry, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3898-3902. doi: 10.1007/s12070-023-03964-2. Epub 2023 Jun 15.

DOI:10.1007/s12070-023-03964-2
PMID:37974735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10646065/
Abstract

Rhinosporidiosis is an endemic condition in India that is difficult to treat when it is disseminated. This condition commonly affects the nasal cavity and nasopharynx mucosa, accounting for 75% of the clinical cases. Although rare, rhinosporidiosis can present with only cutaneous involvement without mucosal disease. Symptoms of this condition include complaints of nasal obstruction and episodic nasal bleeding. Diagnosis is achieved through histopathological examination of tissue and demonstration of the sporangium. Rhinosporidiosis tends to recur as it spreads through autoinoculation. Therefore, during endonasal endoscopic excision of the mass, it is essential not to injure the surrounding mucosa. A trial of medical therapy with dapsone is advised, but it is mostly ineffective in cases of disseminated disease. Here, we present a case report of a patient who underwent seven surgeries for the same condition over 12 years but was unable to get rid of the recurrent menace.

摘要

鼻孢子虫病是印度的一种地方病,播散时难以治疗。这种疾病通常影响鼻腔和鼻咽部黏膜,占临床病例的75%。虽然罕见,但鼻孢子虫病可仅累及皮肤而无黏膜病变。该病的症状包括鼻塞和间歇性鼻出血。通过组织的组织病理学检查和孢子囊的显示来确诊。鼻孢子虫病因自体接种传播而易于复发。因此,在内鼻内镜下切除肿物时,务必不要损伤周围黏膜。建议试用氨苯砜进行药物治疗,但在播散性疾病的病例中大多无效。在此,我们报告一例患者,其在12年里因同一病情接受了7次手术,但仍无法摆脱复发的威胁。

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本文引用的文献

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