Paneru Manisha, Yadav Deepak, Yadav Dhirendra
Department of Otorhinolaryngology, Patan Academy of Health Sciences, Laliptur, Nepal.
Patan Academy of Health Sciences, Lalitpur, Nepal.
Ann Med Surg (Lond). 2025 Feb 11;87(2):1010-1012. doi: 10.1097/MS9.0000000000002898. eCollection 2025 Feb.
Rhinosporidiosis is a chronic granulomatous infection due to and it is endemic mainly in South Asian countries such as India and Sri Lanka. Though it commonly involves nasal and nasopharyngeal mucosa, the involvement of the lacrimal sac is rare. Diagnosis can be done by imaging techniques and confirmed on histopathology.
A 22-year-old male presented with left nasal obstruction and an oropharyngeal mass, without any ocular symptoms. Imaging studies by CT scan revealed a mass involving the nasal and nasolacrimal regions. Biopsy confirmed rhinosporidiosis. The patient underwent a wide local excision of the mass with partial resection of the lacrimal sac. Postoperatively, the patient was given Dapsone for 6 months. Regular follow-up with nasal endoscopy and ophthalmology review showed no evidence of recurrence 1 year following surgery.
Rhinosporidiosis typically presents as vascular polyps in the nasal or ocular areas. It is uncommon that there might be involvement of the lacrimal sac without any symptomatology relevant to the conjunctiva, which has been elaborated in the present case. Examination for the extent of disease is assisted by techniques such as CT and MRI. Histopathology is confirmatory, showing a typical appearance with sporangia filled with multiple endospores. Treatment can be carried out mainly by surgical excision supplemented by electro-coagulation to avoid recurrence. Dapsone post-operatively is recommended as recurrence is common in rhinosporidiosis.
Although rhinosporidiosis predominantly affects the nasal mucosa, lacrimal sac involvement should be considered in the differential diagnosis. Surgical excision along with postoperative medication and regular follow-up forms the mainstay in the management of the disease to avoid recurrence.
鼻孢子虫病是由[病原体未提及]引起的一种慢性肉芽肿性感染,主要流行于印度和斯里兰卡等南亚国家。虽然它通常累及鼻腔和鼻咽部黏膜,但泪囊受累情况罕见。可通过影像学技术进行诊断,并通过组织病理学确诊。
一名22岁男性因左侧鼻塞和口咽部肿物就诊,无任何眼部症状。CT扫描的影像学检查显示肿物累及鼻腔和鼻泪区域。活检确诊为鼻孢子虫病。患者接受了肿物的广泛局部切除及泪囊部分切除术。术后,患者服用氨苯砜6个月。术后1年,定期进行鼻内镜检查和眼科复查,未发现复发迹象。
鼻孢子虫病通常表现为鼻腔或眼部的血管性息肉。泪囊受累而无任何与结膜相关症状的情况并不常见,本病例对此进行了详细阐述。CT和MRI等技术有助于检查疾病的范围。组织病理学具有确诊意义,显示典型表现为充满多个内生孢子的孢子囊。治疗主要通过手术切除,并辅以电凝术以避免复发。由于鼻孢子虫病复发常见,术后推荐使用氨苯砜。
虽然鼻孢子虫病主要影响鼻腔黏膜,但在鉴别诊断时应考虑泪囊受累情况。手术切除、术后药物治疗及定期随访是该病治疗的主要手段,以避免复发。