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混杂因素与精神分裂症所致痴呆

Confounding and the dementia of schizophrenia.

作者信息

Kirkpatrick B, Johnson M, McGuire K, Fletcher R H

出版信息

Psychiatry Res. 1986 Nov;19(3):225-31. doi: 10.1016/0165-1781(86)90101-0.

DOI:10.1016/0165-1781(86)90101-0
PMID:3797549
Abstract

Schizophrenia is often said to cause dementia, and previous studies have found cognitive impairment to be associated with schizophrenia. It is possible, however, that other causes of dementia and the study of patients not representative of all schizophrenics have contributed to these findings. The neuropsychological test scores of 26 schizophrenic outpatients were compared to those of 82 other patients with a history of psychosis. After other known causes of cognitive impairment were controlled for, the schizophrenics were not found to have cognitive impairment when compared to the other patients.

摘要

人们常说精神分裂症会导致痴呆,先前的研究也发现认知障碍与精神分裂症有关。然而,有可能是痴呆的其他病因以及对不具有精神分裂症患者代表性的患者进行的研究导致了这些发现。将26名精神分裂症门诊患者的神经心理学测试分数与82名有精神病病史的其他患者的分数进行了比较。在控制了其他已知的认知障碍病因后,与其他患者相比,未发现精神分裂症患者存在认知障碍。

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