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A double-blind, placebo-controlled, randomized withdrawal trial of sarilumab for the treatment of glucocorticoid-dependent sarcoidosis.一项关于沙瑞鲁单抗治疗糖皮质激素依赖型结节病的双盲、安慰剂对照、随机撤药试验。
Rheumatology (Oxford). 2024 May 2;63(5):1297-1304. doi: 10.1093/rheumatology/kead373.
2
Genetically proxied TYK2 inhibition is associated with reduced sarcoidosis susceptibility.基因代理的酪氨酸激酶2（TYK2）抑制与结节病易感性降低相关。
Ann Rheum Dis. 2023 Mar;82(3):445-446. doi: 10.1136/ard-2022-223513. Epub 2022 Dec 9.
3
Effect of Tocilizumab on Disease Activity in Patients With Active Polymyalgia Rheumatica Receiving Glucocorticoid Therapy: A Randomized Clinical Trial.托珠单抗治疗糖皮质激素治疗的活动性多发性肌痛患者的疾病活动度：一项随机临床试验。
JAMA. 2022 Sep 20;328(11):1053-1062. doi: 10.1001/jama.2022.15459.
4
Genetically proxied IL-6 receptor inhibition and risk of polymyalgia rheumatica.基因代理的白细胞介素-6受体抑制与风湿性多肌痛风险
Ann Rheum Dis. 2022 Sep 12;81(10):1480-1482. doi: 10.1136/annrheumdis-2022-222578.
5
Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile: A Phenome-Wide Association Study.基因下调的白细胞介素-6信号传导与良好的心脏代谢特征相关：一项全表型关联研究。
Circulation. 2021 Mar 16;143(11):1177-1180. doi: 10.1161/CIRCULATIONAHA.120.052604. Epub 2021 Mar 15.
6
Tocilizumab in sarcoidosis patients failing steroid sparing therapies and anti-TNF agents.托珠单抗用于对类固醇节省疗法和抗TNF药物治疗无效的结节病患者。
Respir Med X. 2019;1. doi: 10.1016/j.yrmex.2019.100004. Epub 2019 Feb 21.
7
Sarcoidosis induced by tocilizumab: a paradoxical event?托珠单抗诱发的结节病：一个矛盾的事件？
J Rheumatol. 2013 Oct;40(10):1773-4. doi: 10.3899/jrheum.130278.
8
Increased IL-6 and IL-8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters.结节病患者支气管肺泡灌洗液（BALF）中白细胞介素-6（IL-6）和白细胞介素-8（IL-8）升高：与临床参数的相关性
Clin Exp Immunol. 1997 Jan;107(1):175-81. doi: 10.1046/j.1365-2249.1997.d01-905.x.

IL-6 receptor inhibition and risk of sarcoidosis: a Mendelian randomization study.

作者信息

Zhao Sizheng Steven, Baker Matthew C, Galloway James B

机构信息

Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Science, School of Biological Sciences, Faculty of Biological Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA, USA.

出版信息

Rheumatology (Oxford). 2024 Apr 2;63(4):e118-e119. doi: 10.1093/rheumatology/kead613.

DOI:10.1093/rheumatology/kead613
PMID:37975855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10986795/
Abstract
摘要