Yadav Madhav Prasad, Raju Shobhana, Ballal Sanjana, Bal Chandrasekhar
From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Clin Nucl Med. 2024 Jan 1;49(1):e33-e34. doi: 10.1097/RLU.0000000000004929. Epub 2023 Nov 16.
We present a case involving a 9-year-old boy diagnosed with metastatic carotid body paraganglioma. The metastases were detected in cervical lymph nodes and lungs using 68 Ga-DOTANOC PET/CT imaging. The patient received peptide receptor radionuclide therapy with 177 Lu-DOTATATE. Following 3 treatment cycles, a significant improvement was observed in the metastatic lesions. After 4 cycles, the patient achieved a complete response, with a cumulative administered activity of 16.65 GBq during the therapy. This case underscores the effectiveness of using 177 Lu-DOTATATE in managing metastatic carotid body paraganglioma, offering promising results in terms of tumor regression and overall therapeutic response.
我们报告了一例9岁男孩被诊断为转移性颈动脉体副神经节瘤的病例。使用68 Ga-DOTANOC PET/CT成像在颈部淋巴结和肺部检测到转移灶。该患者接受了177 Lu-DOTATATE肽受体放射性核素治疗。经过3个治疗周期后，转移病灶有显著改善。4个周期后，患者达到完全缓解，治疗期间累积给药活度为16.65 GBq。该病例强调了使用177 Lu-DOTATATE治疗转移性颈动脉体副神经节瘤的有效性，在肿瘤消退和总体治疗反应方面提供了有希望的结果。
