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健康儿童实现最佳睡眠的预测因素:在睡眠延长试验中探索睡眠模式。

Predictors for achieving optimal sleep in healthy children: Exploring sleep patterns in a sleep extension trial.

机构信息

Department of Women's & Children's Health, University of Otago, Dunedin, New Zealand.

Biostatistics Centre, University of Otago, Dunedin, New Zealand.

出版信息

Sleep Health. 2024 Apr;10(2):213-220. doi: 10.1016/j.sleh.2023.09.012. Epub 2023 Nov 18.

Abstract

STUDY OBJECTIVES

Earlier bedtimes can help some children get more sleep, but we don't know which children, or what features of their usual sleep patterns could predict success with this approach. Using data from a randomized crossover trial of sleep manipulation, we sought to determine this.

METHODS

Participants were 99 children aged 8-12years (49.5% female) with no sleep disturbances. Sleep was measured by actigraphy at baseline and over a restriction or extension week (1 hour later or earlier bedtime respectively), randomly allocated and separated by a washout week. Data were compared between baseline (week 1) and extension weeks only (week 3 or 5), using linear or logistic regression analyses as appropriate, controlling for randomization order.

RESULTS

One hour less total sleep time than average at baseline predicted 29.7 minutes (95% CI: 19.4, 40.1) of sleep gained and 3.45 (95% CI: 1.74, 6.81) times higher odds of successfully extending sleep by >30 minutes. Per standardized variable, less total sleep time and a shorter sleep period time were the strongest predictors (significant odds ratios (ORs) of 2.51 and 2.28, respectively). Later sleep offset, more variability in sleep timing and lower sleep efficiency also predicted sleep gains. The sleep period time cut-point that optimized prediction of successful sleep gains was <8 hours 28 minutes with 75% of children's baseline sleep in that range.

CONCLUSIONS

Children with a baseline sleep period time <8½ hours a night obtained the most sleep from earlier bedtimes maintained over a week, demonstrating experimentally the value of earlier bedtimes to improve sleep.

CLINICAL TRIALS REGISTRY

Australian New Zealand Clinical Trial Registry, ACTRN12618001671257, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367587&isReview=true.

摘要

研究目的

早睡有助于一些孩子获得更多的睡眠,但我们不知道哪些孩子,或者他们通常的睡眠模式的哪些特征可以预测这种方法的成功。我们使用睡眠干预的随机交叉试验数据来确定这一点。

方法

参与者为 99 名 8-12 岁的儿童(49.5%为女性),没有睡眠障碍。在基线和限制或延长周(分别提前或推迟 1 小时上床)通过活动记录仪测量睡眠,随机分配并通过洗脱周分开。仅在扩展周(第 3 或 5 周)与基线(第 1 周)进行比较,根据需要使用线性或逻辑回归分析进行比较,控制随机化顺序。

结果

与基线相比,平均总睡眠时间少 1 小时预测可多睡 29.7 分钟(95%CI:19.4,40.1),成功延长睡眠超过 30 分钟的可能性高 3.45 倍(95%CI:1.74,6.81)。在标准化变量中,总睡眠时间越少和睡眠周期时间越短是最强的预测因素(睡眠时间比的显著优势比(OR)分别为 2.51 和 2.28)。较晚的睡眠开始时间、睡眠时间变化较大和睡眠效率较低也预示着睡眠的增加。优化预测成功睡眠增加的睡眠周期时间切点为<8 小时 28 分钟,75%的儿童基线睡眠时间在该范围内。

结论

每晚睡眠时间少于 8 小时 30 分钟的儿童从提前一个星期的早睡中获得最多的睡眠,这从实验上证明了早睡可以改善睡眠。

临床试验注册

澳大利亚新西兰临床试验注册中心,ACTRN12618001671257,https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367587&isReview=true。

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