Institute of Biomedical Engineering, Istanbul University, Istanbul, Turkey.
Division of Gastroenterology, Department of Internal Medicine, Van Education and Research Hospital, Van, Turkey.
Proc Inst Mech Eng H. 2024 Jan;238(1):22-32. doi: 10.1177/09544119231212269. Epub 2023 Nov 20.
Electrogastrography (EGG) is a novel diagnostic modality for assessing the gastrointestinal tract (GI) that generates spontaneous electrical activity and monitors gastric motility. The aim of this study was to compare patients with functional dyspepsia (FD) and diabetic gastroparesis (D-GP) with healthy controls (CT) to use established findings on abnormalities of gastric motility based on EGG characteristics. In this study, 50 patients with FD, 50 D-GP patients, and 50 CT subjects were studied to compare EGG with discrete wavelet transform models (DWT) to extract signal characteristics using a variety of different qualitative and quantitative metrics from pre-prandial and postprandial states. As a result, higher statistically significant ( < 0.05*) were found in the DWT models based on power spectral density (PSD) analysis in both states. We also present that the correlations between EGG metrics and the presence of FD, D-GP, and CT symptoms were inconsistent. This paper represents that EGG assessments of FD and D-GP patients differ from healthy controls in terms of abnormalities of gastric motility. Additionally, we demonstrate that diverse datasets showed adequate gastric motility responses to a meal. We anticipate that our method will provide a comprehensive understanding of gastric motility disorders for better treatment and monitoring in both clinical and research settings. In conclusion, we present potential future opportunities for precise gastrointestinal electrophysiological disorders.
胃电图(EGG)是一种评估胃肠道(GI)的新型诊断方式,它可以产生自发性电活动并监测胃动力。本研究旨在比较功能性消化不良(FD)和糖尿病性胃轻瘫(D-GP)患者与健康对照组(CT),以利用 EGG 特征对胃动力异常的已有发现。在这项研究中,研究了 50 例 FD 患者、50 例 D-GP 患者和 50 例 CT 受试者,以比较 EGG 与离散小波变换模型(DWT),使用各种不同的定性和定量指标从餐前和餐后状态提取信号特征。结果发现,基于功率谱密度(PSD)分析的 DWT 模型在两种状态下均存在更高的统计学显著差异( < 0.05*)。我们还提出,EGG 指标与 FD、D-GP 和 CT 症状之间的相关性不一致。本文代表 FD 和 D-GP 患者的 EGG 评估与健康对照组在胃动力异常方面存在差异。此外,我们证明了不同的数据集显示出对餐食有足够的胃动力反应。我们预计我们的方法将为更好地治疗和监测临床和研究环境中的胃动力障碍提供全面的理解。总之,我们提出了精确胃肠道电生理障碍的潜在未来机会。