Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China.
Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China.
Clin Res Cardiol. 2024 May;113(5):680-693. doi: 10.1007/s00392-023-02328-8. Epub 2023 Nov 20.
Since the first description of apical hypertrophic cardiomyopathy (ApHCM) in 1976, contrasting information from all over the world has emerged regarding the natural history of the disease. However, the recommended guidelines on hypertrophic cardiomyopathy (HCM) pay a cursory reference to ApHCM, without ApHCM-specific recommendations to guide the diagnosis and management. In addition, cardiologists may not be aware of certain aspects that are specific to this disease subtype, and a robust understanding of specific disease features can facilitate recognition and timely diagnosis. Therefore, the review covers the incidence, pathogenesis, and characteristics of ApHCM and imaging methods. Echocardiography and cardiovascular magnetic resonance imaging (CMR) are the most commonly used imaging methods. Moreover, this review presents the management strategies of this heterogeneous clinical entity. In this review, we introduce a novel transapical beating-heart septal myectomy procedure for ApHCM patients with a promising short-time result.
自 1976 年首次描述心尖肥厚型心肌病（ApHCM）以来，世界各地出现了大量关于该病自然病史的对比信息。然而，肥厚型心肌病（HCM）的推荐指南只是粗略地提到了 ApHCM，并没有针对 ApHCM 的具体建议来指导诊断和管理。此外，心脏病专家可能不了解该疾病亚型的某些特定方面，而对特定疾病特征的深入了解有助于识别和及时诊断。因此，本综述涵盖了 ApHCM 的发病率、发病机制和特征以及影像学方法。超声心动图和心血管磁共振成像（CMR）是最常用的影像学方法。此外，本综述还介绍了这种异质临床实体的管理策略。在本综述中，我们为 ApHCM 患者介绍了一种新颖的经心尖跳动心脏室间隔心肌切除术，该手术具有有前途的短期效果。
