Suppr超能文献

前路颈椎间盘切除融合术联合零切迹椎间融合器后吞咽困难的发生率和严重程度:前瞻性研究,随访 3 年。

Incidence and severity of dysphagia after anterior cervical discectomy and fusion with zero-profile spacer: prospective study with 3-years follow-up.

出版信息

Bratisl Lek Listy. 2023;124(12):879-885. doi: 10.4149/BLL_2023_136.

Abstract

INTRODUCTION

Dysphagia after anterior cervical discectomy and fusion (ACDF) is a regular complication. The aim of this study was to identify risk factors for incidence and severity of dysphagia after ACDF with zero-profile spacer.

METHODS

Incidence and severity of dysphagia was evaluated preoperatively and for time of three years after ACDF (regular outpatient check-ups) ‒ prospective study with 3-years follow-up. Severity of dysphagia was assessed subjectively using Bazaz‒Yoo dysphagia score. Influence of selected factors on the incidence and severity of postoperative dysphagia was evaluated. Following statistical methods were used: Fisher's exact test, unpaired Student's t-test, one-way ANOVA and Spearman's correlation coefficient. Level of significance was defined as p ˂ 0.05. Correlations between paired parameters were evaluated according to Spearman's correlation.

RESULTS

Our study included 133 patients who underwent one-, two- or three-level ACDF with zero-profile spacer in years 2013‒2018. Myelopathy and GERD had significant impact on incidence and severity of pre-existing dysphagia. Risk factors for incidence of dysphagia after ACDF were number of treated segments, myelopathy, pre-existing dysphagia and surgery of C4/5 segment. Age of patients, duration of surgery and pre-existing dysphagia correlated positively very weakly to weakly with severity of dysphagia after ACDF. Number of treated segments, myelopathy, GERD and surgery of the C4/5 segment were risk factors for greater severity of postoperative dysphagia.

CONCLUSION

Risk factors for incidence and severity of pre-existing dysphagia were myelopathy and GERD. Risk factors for dysphagia incidence after ACDF were number of treated segments, pre-existing dysphagia, myelopathy and surgery of C4/5 segment (Tab. 6, Fig. 1, Ref. 30).

摘要

简介

颈椎前路椎间盘切除融合术(ACDF)后吞咽困难是一种常见的并发症。本研究旨在确定零切迹椎间融合器(zero-profile spacer)治疗 ACDF 术后吞咽困难发生率和严重程度的相关因素。

方法

采用前瞻性研究方法,对 133 例于 2013 年至 2018 年接受单节段、双节段或三节段 ACDF 治疗的患者进行了为期 3 年的随访,评估术前和术后 3 年(定期门诊检查)吞咽困难的发生率和严重程度。吞咽困难的严重程度采用 Bazaz-Yoo 吞咽困难评分进行主观评估。评估了所选因素对术后吞咽困难发生率和严重程度的影响。采用 Fisher 确切检验、非配对 Student t 检验、单因素方差分析和 Spearman 相关系数进行统计学分析。定义显著性水平为 p<0.05。采用 Spearman 相关分析评估配对参数之间的相关性。

结果

本研究纳入了 133 例接受零切迹椎间融合器治疗的患者,其中单节段、双节段和三节段 ACDF 分别为 133 例、133 例和 133 例。术前存在的脊髓病和胃食管反流病(GERD)对吞咽困难的发生率和严重程度有显著影响。ACDF 术后吞咽困难发生率的危险因素包括治疗节段数、脊髓病、术前存在的吞咽困难和 C4/5 节段手术。患者年龄、手术时间和术前存在的吞咽困难与 ACDF 术后吞咽困难的严重程度呈弱正相关至弱负相关。治疗节段数、脊髓病、GERD 和 C4/5 节段手术是术后吞咽困难严重程度的危险因素。

结论

术前存在吞咽困难的危险因素是脊髓病和 GERD。ACDF 术后吞咽困难发生率的危险因素包括治疗节段数、术前存在的吞咽困难、脊髓病和 C4/5 节段手术(表 6,图 1,参考文献 30)。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验