Department of Chemistry, University of South Florida, Tampa, FL 33620, United States.
College of Science, Hebei Agricultural University, Baoding 071001, Hebei, China.
J Hazard Mater. 2024 Feb 15;464:133017. doi: 10.1016/j.jhazmat.2023.133017. Epub 2023 Nov 16.
In this study, a new fluorine-functionalized covalent organic framework (F-COF) was designed and fabricated by the direct polycondensation of tris(4-aminophenyl)amine and 2,3,5,6-tetra-fluoroterephthaldehyde for the first time. F-COF exhibited a remarkably enhanced adsorption capability compared with that of the fluorine-free COF. The favorable adsorption of aflatoxins was attributed to multiple interactions including pseudo hydrogen bond, F-O, π-π, F-π interactions and hydrophobic interactions between F-COF and aflatoxins. By coupling F-COF based solid phase extraction with high-performance liquid chromatography equipped with fluorescence detector, a rapid and sensitive method for determining aflatoxins (aflatoxin B, B, G and G) in nuts (peanuts and pistachios) was established. Under optimal conditions (35 mg F-COF, 100 mL sample solution, 3 mL min as sample loading rate, pH<7, 0.2 mL acetonitrile as desorption solvent), the limits of detection for aflatoxins were 0.02-0.30 ng g. The linear range was 0.08-16.0 ng g and the recoveries of the F-COF-based method were 83.5-114 % with relative standard deviations less than 8.0 %.
在这项研究中，首次通过三（4-氨基苯基）胺和 2,3,5,6-四氟对苯二甲醛的直接缩聚设计和制备了一种新型的氟功能化共价有机框架（F-COF）。与无氟 COF 相比，F-COF 表现出显著增强的吸附能力。黄曲霉毒素的良好吸附归因于多种相互作用，包括拟氢键、F-O、π-π、F-π 相互作用以及 F-COF 和黄曲霉毒素之间的疏水相互作用。通过将基于 F-COF 的固相萃取与配备荧光检测器的高效液相色谱法相结合，建立了一种快速灵敏测定坚果（花生和开心果）中黄曲霉毒素（黄曲霉毒素 B、B、G 和 G）的方法。在最佳条件下（35 mg F-COF、100 mL 样品溶液、3 mL min 的样品加载速率、pH<7、0.2 mL 乙腈作为洗脱溶剂），黄曲霉毒素的检出限为 0.02-0.30 ng g。线性范围为 0.08-16.0 ng g，基于 F-COF 的方法的回收率为 83.5-114%，相对标准偏差小于 8.0%。
