Loyola University Chicago, Stritch School of Medicine, Chicago, Illinois.
Loyola University Chicago, Clinical Research Office Biostatistics Collaborative Core, Chicago, Illinois.
Clin Med Res. 2023 Sep;21(3):129-135. doi: 10.3121/cmr.2023.1817.
To examine disparities between primary care provider (PCP) and gastroenterologist diagnosis and management of irritable bowel syndrome (IBS). Retrospective cross-sectional study. A 547-bed quaternary-care hospital within the Loyola University Healthcare System. 1000 patients aged 18-65 with an ICD-10 diagnosis of IBS We randomly selected 1000 patients aged 18 to 65 years within the Loyola University Healthcare System's electronic medical record with an ICD-10 diagnosis of IBS. Physician notes and diagnostic results were reviewed for documentation of symptoms fulfilling Rome IV criteria and resolution of symptoms. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of primary diagnoses assigned by PCPs and gastroenterologists were assessed along with number of diagnostic tests ordered. The mean age (SD) was 45 (12) years, and 76.9% were female. Sensitivity of an IBS diagnosis by a PCP was 77.6% (95% CI 73.3-81.9), compared with 60.1% (95% CI 54.7-65.6) for a gastroenterologist. Specificity of an IBS diagnosis by a PCP was 27.5% (95% CI 23.5-31.5), compared with 71.1% (95% CI 64.6-77.5) for a gastroenterologist diagnosis of IBS. A gastroenterologist diagnosis of IBS carried a high PPV (77.3%, 95% CI 72.0-82.6) compared with 44.6% (95% CI 40.7-48.5) for a PCP. Of 180 patients with outcome data, 69.4% had resolution of symptoms at follow-up. The sensitivity of gastroenterologist diagnosis of IBS closely matches the sensitivity of Rome IV criteria in validation studies. The high specificity and PPV of gastroenterologists suggest more cautious diagnosis by gastroenterologists, with PCPs more likely to assign a diagnosis of IBS incorrectly or without sufficient documentation of symptoms fulfilling Rome IV criteria. Reported resolution rates suggest primary care management of IBS is appropriate, but PCPs may benefit from gastroenterologist consultation and diagnostic guidelines for greater specificity in diagnosing IBS.
为了研究初级保健提供者 (PCP) 和胃肠病学家在诊断和治疗肠易激综合征 (IBS) 方面的差异。回顾性横断面研究。洛约拉大学医疗保健系统内的一家拥有 547 张床位的四级保健医院。1000 名年龄在 18-65 岁之间的 IBS 患者
我们在洛约拉大学医疗保健系统的电子病历中随机选择了 1000 名年龄在 18 至 65 岁之间的 IBS 患者,他们的 ICD-10 诊断为 IBS。对医生的笔记和诊断结果进行了审查,以记录符合罗马 IV 标准的症状和症状缓解情况。评估了 PCP 和胃肠病学家诊断的主要诊断的敏感性、特异性、阳性预测值 (PPV) 和阴性预测值 (NPV),以及所开诊断测试的数量。平均年龄 (SD) 为 45(12)岁,76.9%为女性。PCP 诊断 IBS 的敏感性为 77.6%(95%CI 73.3-81.9),而胃肠病学家的敏感性为 60.1%(95%CI 54.7-65.6)。PCP 诊断 IBS 的特异性为 27.5%(95%CI 23.5-31.5),而胃肠病学家的特异性为 71.1%(95%CI 64.6-77.5)。与 PCP 相比,胃肠病学家诊断的 IBS 具有较高的 PPV(77.3%,95%CI 72.0-82.6),而 PCP 的 PPV 为 44.6%(95%CI 40.7-48.5)。在有结果数据的 180 名患者中,69.4%的患者在随访时症状缓解。胃肠病学家诊断 IBS 的敏感性与罗马 IV 标准在验证研究中的敏感性非常吻合。胃肠病学家的高特异性和 PPV 表明胃肠病学家的诊断更为谨慎,而 PCP 更有可能错误地或没有充分记录符合罗马 IV 标准的症状而诊断为 IBS。报告的缓解率表明初级保健管理 IBS 是合适的,但 PCP 可能受益于胃肠病学家的咨询和诊断指南,以提高 IBS 诊断的特异性。