National University of Singapore, Singapore
National University of Singapore, Singapore.
Clin Med Res. 2023 Sep;21(3):122-128. doi: 10.3121/cmr.2023.1819.
Epidemiological outcomes of renal cell carcinoma (RCC) remain sparse. This study aims to compare preoperative characteristics, surgical outcomes, and oncological outcomes of RCC patients at a urology unit in Singapore. A retrospective cohort analysis of 137 RCC patients in the National University Hospital of Singapore who had undergone partial nephrectomy between 2009 and 2020 was conducted. χ tests (Chi-Square Test, Fisher's Exact Test) and one-way analysis of variance (ANOVA) were used for comparing categorical and continuous variables respectively. Kaplan-Meier estimates were used for survival analysis. In total, 137 patients were identified (Chinese [n=82], Malay [n=19], Indian [n=15], Others [n=21]). Indian patients were diagnosed at an earlier age (52.13±10.52 years, =0.018). A larger percentage of Malay patients (78.9%, <0.001) were operated on before 2016, prior to the center's adoption of the robotic surgical technique. More Malay and Indian patients underwent laparoscopic surgery (36.8% and 46.7%, =0.008), experiencing higher rates of intra-operative conversions compared to the Chinese and other ethnicities (5.3% and 13.3% vs. 0%, =0.011). They also had longer post-operative stays compared to Chinese (7.42±6.46 days; 7.40±7.69 days vs. 4.88±2.87 days, =0.036). Malays were much less likely to undergo robotic partial nephrectomy compared to Chinese patients (OR=0.295, 95% CI=0.102-0.856) and had the highest rate of metastatic recurrence (10.5%, =0.023).
新加坡某泌尿科对肾细胞癌(RCC)患者的术前特征、手术结果和肿瘤学结果进行比较。回顾性分析了 2009 年至 2020 年间在新加坡国立大学医院接受部分肾切除术的 137 例 RCC 患者。使用卡方检验(Chi-Square 检验,Fisher 确切检验)和单因素方差分析(One-way ANOVA)分别比较分类变量和连续变量。使用 Kaplan-Meier 估计进行生存分析。共纳入 137 例患者(中国人 [n=82],马来人 [n=19],印度人 [n=15],其他人 [n=21])。印度患者的诊断年龄较小(52.13±10.52 岁,=0.018)。在该中心采用机器人手术技术之前,有较大比例的马来患者(78.9%,<0.001)在 2016 年之前接受手术。更多的马来人和印度患者接受了腹腔镜手术(36.8%和 46.7%,=0.008),与中国和其他种族相比,中转开腹率更高(5.3%和 13.3%比 0%,=0.011)。与中国患者相比,他们的术后住院时间也更长(7.42±6.46 天;7.40±7.69 天 vs. 4.88±2.87 天,=0.036)。与中国患者相比,马来患者接受机器人部分肾切除术的可能性小得多(OR=0.295,95%CI=0.102-0.856),且转移复发率最高(10.5%,=0.023)。