Dahourou Laibané Dieudonné, Akio Salimata, Savadogo Madi, Yougbaré Bernadette, Ouoba Lalidia Bruno, Tapsoba Arnaud Stéphane Rayangnéwêndé, Zerbo Lamouni Habibata, Ilboudo Abdoul Kader, Abga Roland Lamoussa, Traoré Amadou, Dione Michel Mainack, Bada Alambédji Rianatou
Institut des Sciences de l'Environnement et du Développement Rural (ISEDR), Université de Dédougou, Dédougou, Burkina Faso.
Laboratoire de Biologie et santé animales (LABIOSA), Institut de l'Environnement et de recherches Agricoles (INERA), Ouagadougou, Burkina Faso.
Vet Med Sci. 2023 Nov 20;10(2). doi: 10.1002/vms3.1322.
Crimean-Congo haemorrhagic fever (CCHF) is caused by an orthonairovirus transmitted by bites from infected ticks or by direct contact with blood or tissues of infected ticks, viraemic patients or viraemic livestock.
It was implemented to access the seropositivity and associated factors with CCHF in sheep in two provinces in Burkina Faso.
Three hundred and sixty-four sheep sera have been taken from 73 herds in four municipalities and two provinces. The double-antigen sandwich ELISA test was used to test for antibodies against CCHF virus (CCHFV). Data have also been collected using questionnaire to assess factors associated with CCHF seropositivity.
Fifty-four (54 out to 364 sheep were seropositive given an overall seropositivity of 14.8% (95% confidence interval [CI]: 10.9%-19.8%) with an adjusted seropositivity of 13.1%. The study showed that 15.6% (95% CI: 10.2-21.0) and 14.1% (95% CI: 9.2-19.1) of sheep in the provinces of Mouhoun and Kénédougou, respectively, had antibodies against CCHFV. The highest seropositivity was found in Dédougou municipality (24.4%). The study showed that sheep from the municipalities of Dédougou (AOR = 8.4; 95% CI: 2.2-31.8), N'dorola (AOR = 14.7; 95% CI: 3.8-56.8), Sindou (AOR = 4.9; 95% CI: 1.2-20.7), sheep aged between 27 and 36 months (AOR = 6.4; 95% CI: 2.3-17.3) and sheep with ticks (AOR = 24.8; 95% CI: 7.7-80.1) were more likely to be seropositive to CCHF.
The study revealed that sheep in Burkina Faso experienced contacts with CCHFV and suggests the importance of implementing control action in the country.
克里米亚-刚果出血热（CCHF）由正布尼亚病毒引起，通过被感染蜱虫叮咬或直接接触受感染蜱虫、病毒血症患者或病毒血症家畜的血液或组织传播。
在布基纳法索两个省对绵羊进行CCHF血清阳性率及相关因素的研究。
从四个市两个省的73个畜群中采集了364份绵羊血清。采用双抗原夹心ELISA试验检测抗CCHF病毒（CCHFV）抗体。还通过问卷调查收集数据，以评估与CCHF血清阳性相关的因素。
364份绵羊血清中有54份呈血清阳性，总体血清阳性率为14.8%（95%置信区间[CI]：10.9%-19.8%），校正后血清阳性率为13.1%。研究表明，穆洪省和凯内杜古省分别有15.6%（95%CI：10.2-21.0）和14.1%（95%CI：9.2-19.1）的绵羊有抗CCHFV抗体。血清阳性率最高的是代杜古市（24.4%）。研究表明，来自代杜古市（比值比[AOR]=8.4；95%CI：2.2-31.8）、恩多罗拉市（AOR=14.7；95%CI：3.8-56.8）、辛杜市（AOR=4.9；95%CI：1.2-20.7）的绵羊，年龄在27至36个月之间的绵羊（AOR=6.4；95%CI：2.3-17.3）以及身上有蜱虫的绵羊（AOR=24.8；95%CI：7.7-80.1）更有可能CCHF血清呈阳性。
该研究表明布基纳法索的绵羊接触过CCHFV，并提示在该国采取防控措施的重要性。
