Environmental Sciences and Rural Development Institute (ISEDR), Daniel Muezzin Coulibaly University, Dedougou, Burkina Faso.
Animal Biology and Health Laboratory (LABIOSA), Institute of Environment and Agricultural Research (INERA), Ouagadougou, Burkina Faso.
Open Vet J. 2024 Aug;14(8):1912-1920. doi: 10.5455/OVJ.2024.v14.i8.19. Epub 2024 Aug 31.
Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease caused by an Orthonairovirus of the Nairoviridae family transmitted by tick bites and also contact with infected blood, tissues, or body fluids. Until now, fewer studies have been conducted on animals in Burkina Faso.
This study was conducted to investigate the seroprevalence and risk factors of CCHF in two provinces of Burkina Faso.
Serum samples were collected from 371 bovine animals. In addition, questionnaire surveys were performed with cattle breeders. The double-antigen sandwich enzyme-linked immunosorbent assay test was used to determine the presence of antibodies against the CCHF virus in serum samples.
The results showed an overall prevalence of 72.2% [95% confidence interval (CI): 67.6%-76.7%)]. Within the 74 herds included in the study, a herd prevalence of 96% (95% CI: 91.4%-100%) was obtained. The prevalence was significantly higher in Mouhoun province (80%, 95% CI: 74%-86%) compared to Kénédougou province (65.6%, 95% CI: 59.1%-72.2%). Multivariable regression analysis showed that females were more likely to be infected (OR = 1.99, 95% CI: 1.1-3.6, = 0.023) than males. In addition, cross-breed animals (OR = 6.42, 95% CI: 1.71-24.14, = 0.006) were more likely to be infected compared to local-bred animals. This study revealed the presence of antibodies of the CCHF virus in cattle in the study area, indicating the need to implement control measures in the veterinary sector.
Despite the importance of CCHF in public health, no study has been implemented regarding this condition in animals in Burkina Faso. This study described evidence of cattle exposure to the virus in Burkina Faso.
克里米亚-刚果出血热（CCHF）是一种由纳伊罗病毒科的 Orthonairovirus 引起的人畜共患病，通过蜱叮咬以及接触受感染的血液、组织或体液传播。到目前为止，在布基纳法索对动物进行的研究较少。
本研究旨在调查布基纳法索两个省份的 CCHF 血清阳性率和危险因素。
采集了 371 份牛血清样本。此外，还对牛饲养员进行了问卷调查。使用双抗原夹心酶联免疫吸附试验（ELISA）检测血清样本中是否存在抗 CCHF 病毒的抗体。
结果显示，总体阳性率为 72.2%[95%置信区间（CI）：67.6%-76.7%]。在所研究的 74 个牛群中，牛群阳性率为 96%（95%CI：91.4%-100%）。在穆洪省（80%，95%CI：74%-86%）的阳性率明显高于肯内杜古省（65.6%，95%CI：59.1%-72.2%）。多变量回归分析显示，雌性比雄性更容易感染（OR=1.99，95%CI：1.1-3.6， = 0.023）。此外，与本地品种相比，杂交动物（OR=6.42，95%CI：1.71-24.14， = 0.006）更有可能感染该病毒。本研究表明，在研究区域的牛群中存在 CCHF 病毒的抗体，这表明需要在兽医部门实施控制措施。
尽管 CCHF 对公共卫生很重要，但在布基纳法索，尚未针对动物进行此项研究。本研究描述了布基纳法索牛群接触该病毒的证据。
