Osteoporosis Prevention and Treatment Center, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, United States.
Division of Endocrinology and Metabolism, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
J Clin Densitom. 2024 Jan-Mar;27(1):101436. doi: 10.1016/j.jocd.2023.101436. Epub 2023 Oct 31.
The precision for spine bone mineral density (BMD) worsens as vertebrae are excluded, so recommendations are needed for least significant change (LSC) for spine BMDs based on fewer than 4 vertebrae. The task force recommends re-analysis of each facility's L1-L4 in-house precision study to determine the precision in order to calculate the LSC for each combination of 2 or 3 reported vertebrae. The task force recommended not reporting spine BMDs based on single vertebral bodies for either the diagnosis or monitoring of osteoporosis. Specific data for studies assessing the precision of two non-contiguous vertebrae are mixed, but ultimately the task force recommended that spine BMD based on 2 non-contiguous vertebrae can be used for the diagnosis and monitoring of osteoporosis.
脊柱骨密度 (BMD) 的精确性随着椎体的排除而降低，因此需要针对少于 4 个椎体的脊柱 BMD 制定最小有意义变化 (LSC) 的建议。该工作组建议重新分析每个机构的 L1-L4 内部精密度研究，以确定精度，从而计算出每个报告的 2 或 3 个椎体组合的 LSC。该工作组建议不要根据单个椎体报告脊柱 BMD，无论是用于骨质疏松症的诊断还是监测。评估两个不连续椎体的精确性的具体数据是混杂的，但最终工作组建议，基于两个不连续椎体的脊柱 BMD 可用于骨质疏松症的诊断和监测。
