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口腔内潜在感染灶及其对中枢神经系统脓肿形成的影响:文献综述。

Potential infection foci in the oral cavity and their impact on the formation of central nervous system abscesses: A literature review.

机构信息

Department of Cranio-Maxillofacial and Oral Surgery and Implantology, Infant Jesus Clinical Hospital-University Clinical Center of the Medical University of Warsaw, Warsaw, Poland.

Department of Adult Infectious Diseases, Medical University of Warsaw, Warsaw, Poland.

出版信息

Medicine (Baltimore). 2023 Nov 17;102(46):e35898. doi: 10.1097/MD.0000000000035898.

DOI:10.1097/MD.0000000000035898
PMID:37986318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10659677/
Abstract

Despite advancements in preventive, diagnostic, and therapeutic activities in medicine, inflammatory processes of the central nervous system remain a significant problem, posing a serious threat to life and health. Purulent central nervous system infections are unique, including abscesses of the brain and spine, which are severe infections occurring in 0.4% to 0.9% of 1000 patients worldwide. Central nervous system abscesses have varying etiology. For example, organized, encapsulated abscesses of the brain are a unique group of inflammatory processes in the central nervous system caused by inflammation around the teeth in 3% to 10% of cases. Sometimes, the condition of patients with brain abscesses is severe and life-threatening. Therefore, detecting and eliminating all causes early, including those potentially resulting from odontogenic infections, is important; accurate and early diagnosis enables appropriate treatment. This paper presents a review of the information available in the literature on brain abscesses and their relationship with odontogenic foci of infection in the oral cavity.

摘要

尽管医学在预防、诊断和治疗方面取得了进步,但中枢神经系统的炎症仍是一个重大问题,对生命和健康构成严重威胁。化脓性中枢神经系统感染是一种独特的疾病,包括脑脓肿和脊髓脓肿,在全球范围内,每 1000 名患者中就有 0.4%至 0.9%会发生这种严重感染。中枢神经系统脓肿的病因各不相同。例如,由牙齿周围炎症引起的、有组织的、有包膜的脑脓肿是中枢神经系统炎症的一个独特类型,在 3%至 10%的病例中出现。有时,脑脓肿患者的病情严重且危及生命。因此,早期发现和消除所有病因很重要,包括那些可能由牙源性感染引起的病因;准确和早期的诊断可以实现恰当的治疗。本文综述了文献中关于脑脓肿及其与口腔牙源性感染灶之间关系的信息。

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Case Rep Infect Dis. 2022 Jan 4;2022:5140259. doi: 10.1155/2022/5140259. eCollection 2022.
2
Brain abscess of odontogenic origin in patients with malignant tumors: A report of two cases.恶性肿瘤患者牙源性脑脓肿:两例报告。
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3
Brain abscess and periodontal pathogens (). Report of a case.脑脓肿与牙周病原体(病例报告)
Clin Case Rep. 2020 Aug 2;8(12):2488-2493. doi: 10.1002/ccr3.3173. eCollection 2020 Dec.
4
The Bacterial Connection between the Oral Cavity and the Gut Diseases.口腔与肠道疾病的细菌关联。
J Dent Res. 2020 Aug;99(9):1021-1029. doi: 10.1177/0022034520924633. Epub 2020 May 28.
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Interaction of Oral and Toothbrush Microbiota Affects Oral Cavity Health.口腔和牙刷微生物群的相互作用影响口腔健康。
Front Cell Infect Microbiol. 2020 Feb 4;10:17. doi: 10.3389/fcimb.2020.00017. eCollection 2020.
6
Brain Abscess Secondary to a Dental Infection.牙源性脑脓肿
Case Rep Emerg Med. 2020 Feb 6;2020:3248174. doi: 10.1155/2020/3248174. eCollection 2020.
7
Retrospective analysis of brain abscess in 183 patients: A 10-year survey.183例脑脓肿患者的回顾性分析:一项为期10年的调查。
Medicine (Baltimore). 2019 Nov;98(46):e17670. doi: 10.1097/MD.0000000000017670.
8
Multiple brain abscesses treated by extraction of the maxillary molars with chronic apical lesion to remove the source of infection.通过拔除患有慢性根尖病变的上颌磨牙以去除感染源来治疗多发性脑脓肿。
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Brain abscess of odontogenic origin in children: a systematic review of the literature with emphasis on therapeutic aspects and a new case presentation.儿童牙源性脑脓肿:文献系统综述,重点关注治疗方面及1例新病例报告
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