Emerg Infect Dis. 2023 Dec;29(12):2488-2497. doi: 10.3201/eid2912.230594.
Japanese encephalitis (JE) is associated with an immense social and economic burden. Published cost-of-illness data come primarily from decades-old studies. To determine the cost of care for patients with acute JE and initial and long-term sequelae from the societal perspective, we recruited patients with laboratory-confirmed JE from the past 10 years of JE surveillance in Bangladesh and categorized them as acute care, initial sequalae, and long-term sequelae patients. Among 157 patients, we categorized 55 as acute, 65 as initial sequelae (53 as both categories), and 90 as long-term sequelae. The average (median) societal cost of an acute JE episode was US $929 ($909), of initial sequelae US $75 ($33), and of long-term sequelae US $47 ($14). Most families perceived the effect of JE on their well-being to be extreme and had sustained debt for JE expenses. Our data about the high cost of JE can be used by decision makers in Bangladesh.
日本脑炎 (JE) 给社会带来了巨大的经济负担。已发表的疾病成本数据主要来自于几十年前的研究。为了从社会角度确定急性 JE 患者的护理成本以及初始和长期后遗症的成本,我们从孟加拉国过去 10 年的 JE 监测中招募了经实验室确诊的 JE 患者,并将他们分为急性护理、初始后遗症和长期后遗症患者。在 157 名患者中,我们将 55 名归类为急性,65 名归类为初始后遗症(53 名同时属于这两类),90 名归类为长期后遗症。急性 JE 发作的平均(中位数)社会成本为 929 美元(909 美元),初始后遗症为 75 美元(33 美元),长期后遗症为 47 美元(14 美元)。大多数家庭认为 JE 对其幸福感的影响非常严重,并且因为 JE 支出而持续负债。我们关于 JE 高成本的数据可被孟加拉国的决策者使用。