Emerg Infect Dis. 2023 Dec;29(12):2563-2565. doi: 10.3201/eid2912.231114.
During 2015-2022, a genetic cluster of OXA-48-producing uropathogenic Escherichia coli sequence type 127 spread throughout the Netherlands. The 20 isolates we investigated originated mainly from urine, belonged to Clermont phylotype B2, and carried 18 genes encoding putative uropathogenicity factors. The isolates were susceptible to first-choice antimicrobial drugs for urinary tract infections.
在 2015 年至 2022 年期间,产 OXA-48 的尿路致病性大肠杆菌序列类型 127 的基因簇在整个荷兰传播。我们研究的 20 株分离株主要来源于尿液,属于 Clermont phylotype B2,并携带 18 个编码假定尿路致病性因子的基因。这些分离株对用于治疗尿路感染的首选抗菌药物敏感。