Ražić Slavica, Gadžurić Slobodan, Trtić-Petrović Tatjana
Department of Analytical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, Belgrade, Serbia.
Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, Novi Sad, Serbia.
Anal Bioanal Chem. 2024 Apr;416(9):2023-2029. doi: 10.1007/s00216-023-05045-3. Epub 2023 Nov 22.
The widespread use of ionic liquids (ILs) as greener solvents in analytical sciences, especially in sample pretreatment, has focused attention on exploiting their enormous potential, not only on eliminating and improving the drawbacks faced by scientists. These ionic compounds with unique physicochemical properties can be tuned through smart synthesis, combining cations and anions, so that the compound exhibits excellent properties for its intended purpose. Ionic liquids are rightly referred to as designer solvents. Validation of a newly proposed analytical methods using ionic liquids, either in sample preparation or in further analysis, is a critical process to demonstrate that a particular analytical method is fit for purpose and provides reliable and accurate results. In addition, this article specially addressed the potential toxicity of ionic liquids with the modest goal of assisting researchers in this field by expanding their target areas.
离子液体（ILs）作为一种更环保的溶剂在分析科学领域，尤其是在样品预处理中得到广泛应用，这不仅使人们关注到要挖掘其巨大潜力，还要消除和改善科学家们面临的缺点。这些具有独特物理化学性质的离子化合物可以通过巧妙的合成方法进行调整，将阳离子和阴离子结合起来，从而使该化合物展现出符合其预期用途的优异性能。离子液体被恰当地称为定制溶剂。在样品制备或进一步分析中，验证新提出的使用离子液体的分析方法是一个关键过程，以证明特定的分析方法是否适用并能提供可靠准确的结果。此外，本文特别探讨了离子液体的潜在毒性，目标较为适度，旨在通过扩大研究领域来帮助该领域的研究人员。
