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肥胖问题圆桌会议:肥胖与东亚人群

Obesity Pillars Roundtable: Obesity and East Asians.

作者信息

Bays Harold Edward, Ng Jennifer, Sicat Jeffrey, Look Michelle

机构信息

Diplomate of American Board of Obesity Medicine, Medical Director / President Louisville Metabolic and Atherosclerosis Research Center, Clinical Associate Professor / University of Louisville Medical School, 3288 Illinois Avenue, Louisville, KY, 40213, USA.

Diplomate of American Board of Obesity Medicine, 234 East 85 Street, 6 Floor, New York, NY, 10028, USA.

出版信息

Obes Pillars. 2022 Mar 12;2:100011. doi: 10.1016/j.obpill.2022.100011. eCollection 2022 Jun.

Abstract

BACKGROUND

Individuals from East Asia make up about 1/5 of the world's population. Individuals from South Asia with obesity are well-described to have increased susceptibility to cardiovascular disease (CVD) risk factors and increased risk of CVD events. Less well described are the adiposopathic effects of the disease of obesity among East Asians.

METHODS

This roundtable discussion includes 3 obesity medicine specialists with experience in the clinical management of obesity among patients of East Asian descent. Included are citations regarding obesity and East Asians.

RESULTS

In general, East Asians are at decreased risk for CVD compared to Whites and South Asians. However, compared to Whites, for the same body mass index, East Asians are at increased risk for metabolic diseases such as type 2 diabetes mellitus. Both obesity and type 2 diabetes mellitus are epidemics in East Asian countries. In this Roundtable, the panelists discuss East Asian nutrition and physical activity, with special attention given to Asian foods, especially rice. The panelists also discuss East Asian genetic predispositions for development of visceral adiposity, type 2 diabetes mellitus, as well as genetic predisposition to drug metabolism and potential drug and herbal interactions, as commonly encountered in patients with obesity. Finally, the panelists give summary tips for managing East Asian patients with obesity.

CONCLUSION

The three panelists of this roundtable describe their practical diagnostic processes and treatment plans for patients from East Asia, with an emphasis on a patient-centered approach to obesity in this unique population.

摘要

背景

东亚人群约占世界人口的五分之一。南亚肥胖个体被充分描述为对心血管疾病(CVD)风险因素的易感性增加以及CVD事件风险增加。而东亚人群中肥胖疾病的脂肪病变影响则较少被描述。

方法

本次圆桌讨论包括3位在东亚裔患者肥胖临床管理方面有经验的肥胖医学专家。其中包含了关于肥胖与东亚人群的文献引用。

结果

总体而言,与白人和南亚人相比,东亚人患心血管疾病的风险较低。然而,与白人相比,在相同体重指数下,东亚人患2型糖尿病等代谢疾病的风险增加。肥胖和2型糖尿病在东亚国家均为流行病。在本次圆桌会议中,小组成员讨论了东亚人的营养和身体活动情况,特别关注亚洲食物,尤其是大米。小组成员还讨论了东亚人内脏肥胖、2型糖尿病发生的遗传易感性,以及肥胖患者中常见的药物代谢遗传易感性和潜在的药物与草药相互作用。最后,小组成员给出了管理东亚肥胖患者的总结性建议。

结论

本次圆桌会议的三位小组成员描述了他们针对东亚患者的实际诊断过程和治疗计划,强调在这一独特人群中以患者为中心的肥胖治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64a6/10662030/e5610f8c5dd7/fx1.jpg

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