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前瞻性随机对照试验研究杏仁对面部皱纹和色素沉着的影响。

Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation.

机构信息

Department of Dermatology, University of California-Davis, Sacramento, CA 95816, USA.

Department of Dermatology, Southern Illinois University, Springfield, IL 62901, USA.

出版信息

Nutrients. 2021 Feb 27;13(3):785. doi: 10.3390/nu13030785.

DOI:10.3390/nu13030785
PMID:33673587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7997170/
Abstract

BACKGROUND

Almonds have long been studied as a rich source of fatty acids, phytochemical polyphenols and antioxidants such as vitamin E. A recent study compared almond supplementations to a calorie-matched intervention for 16 weeks, yielding statistically significant improvement in wrinkle severity in postmenopausal women with Fitzpatrick skin types I and II that received almonds. This study furthers that assessment with a larger population and duration of 24 weeks to assess the influence of almond consumption on wrinkle severity, skin pigmentation and other skin biophysical profiles.

OBJECTIVE

To investigate the effects of almond consumption on photoaging such as wrinkles and pigment intensity as well as facial biophysical parameters such as sebum production, skin hydration and water loss.

DESIGN AND INTERVENTIONS

A prospective, randomized controlled study assessed postmenopausal women with Fitzpatrick skin types I or II who consumed 20% of their daily energy consumption in either almonds or a calorie-matched snack for 24 weeks. A facial photograph and image analysis system was used to obtain standardized high-resolution photographs and information on wrinkle width and severity at 0, 8, 16 and 24 weeks. Measurements of transepidermal water loss (TEWL), skin pigmentation, skin hydration and sebum production were also completed at each visit.

RESULTS

The average wrinkle severity was significantly decreased in the almond intervention group at week 16 and week 24 compared to baseline by 15% and 16%, respectively. Facial pigment intensity was decreased 20% in the almond group at week 16 and this was maintained by week 24. There were no significant differences in skin hydration or TEWL in the almond group compared to the control, although sebum excretion was increased in the control group.

CONCLUSION

The daily consumption of almonds may improve several aspects of photoaging such as facial wrinkles and pigment intensity in postmenopausal women. In conclusion, the daily consumption of almonds may contribute to the improvement of facial wrinkles and reduction of skin pigmentation among postmenopausal women with Fitzpatrick skin types I and II.

摘要

背景

杏仁一直被研究为富含脂肪酸、植物化学多酚和抗氧化剂(如维生素 E)的来源。最近的一项研究比较了杏仁补充剂与卡路里匹配的干预措施,结果发现,接受杏仁补充剂的菲茨帕特里克皮肤类型 I 和 II 的绝经后妇女的皱纹严重程度有统计学意义的改善。本研究通过更大的人群和 24 周的研究时间进一步评估了杏仁的摄入对皱纹严重程度、皮肤色素沉着和其他皮肤生物物理特征的影响。

目的

调查杏仁摄入对皱纹和色素强度等光老化以及皮脂分泌、皮肤水分和水分流失等面部生物物理参数的影响。

设计和干预

一项前瞻性、随机对照研究评估了菲茨帕特里克皮肤类型 I 或 II 的绝经后妇女,她们在 24 周内每天摄入 20%的能量来自杏仁或卡路里匹配的零食。使用面部照片和图像分析系统获得标准化的高分辨率照片,并在 0、8、16 和 24 周时获得皱纹宽度和严重程度的信息。还在每次就诊时测量经表皮水分流失 (TEWL)、皮肤色素沉着、皮肤水分和皮脂分泌。

结果

杏仁干预组在第 16 周和第 24 周时,皱纹严重程度分别比基线时下降了 15%和 16%,平均皱纹严重程度显著下降。杏仁组在第 16 周时面部色素强度下降了 20%,第 24 周时仍保持不变。与对照组相比,杏仁组的皮肤水分或 TEWL 没有显著差异,但对照组的皮脂分泌增加。

结论

杏仁的日常摄入可能会改善绝经后妇女的皮肤皱纹和色素沉着等几个方面的光老化问题。综上所述,杏仁的日常摄入可能有助于改善菲茨帕特里克皮肤类型 I 和 II 的绝经后妇女的面部皱纹和减少皮肤色素沉着。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/b03bc03e13d5/nutrients-13-00785-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/1c0baa61718b/nutrients-13-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/5e602cdee587/nutrients-13-00785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/7c81fa9ffb0f/nutrients-13-00785-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/301b23654433/nutrients-13-00785-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/1723fbd822b2/nutrients-13-00785-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/513bf8117eb6/nutrients-13-00785-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/b03bc03e13d5/nutrients-13-00785-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/1c0baa61718b/nutrients-13-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/5e602cdee587/nutrients-13-00785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/7c81fa9ffb0f/nutrients-13-00785-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/301b23654433/nutrients-13-00785-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/1723fbd822b2/nutrients-13-00785-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/513bf8117eb6/nutrients-13-00785-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c85/7997170/b03bc03e13d5/nutrients-13-00785-g007.jpg

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