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在疫情期间使用口罩是否会加重玫瑰痤疮?

Has the Use of the Mask Exacerbated Rosacea During the Pandemic?

作者信息

Trave Ilaria, Salvi Ilaria, Cozzani Emanuele, Donadoni Rebecca, Parodi Aurora

机构信息

Section of Dermatology - Department of Health Sciences, University of Genoa, IRCCS - Ospedale Policlinico San Martino, Genoa, Italy.

出版信息

Dermatol Pract Concept. 2023 Oct 1;13(4):e2023230. doi: 10.5826/dpc.1304a230.

Abstract

INTRODUCTION

During the COVID-19 pandemic, personal protective equipment, particularly face masks, became an essential requirement to engage in various activities. Several articles reported an increase of recurrences of dermatologic facial diseases (ie, acne, rosacea) related to mask use.

OBJECTIVES

To evaluate the number of recurrences of rosacea related to face mask use.

METHODS

This prospective study was conducted on adult patients with a pre-pandemic diagnosis of mild and moderate papulopustular rosacea. All patients had previously achieved either partial or complete remission after a 4-month treatment with topical ivermectin in 2019. We collected data in two different phases characterized by different intensity of mask use during the pandemic and post-pandemic period. We collected data through clinical assessment of the disease, questionnaires on personal habits and standardized skin surface biopsy to study the Demodex mites count.

RESULTS

We enrolled a total of 30 patients. In the pandemic period, 5/30 patients had a relapse of mild papulopustular rosacea; the Demodex sample resulted positive in 4/5 relapsed patients. In the post-pandemic period, 4/30 patients reported a relapse of mild rosacea (3 patients) and moderate papulopustular rosacea (1 patient). At the Demodex exam, 1/4 relapsed patients resulted positive.

CONCLUSIONS

We did not find a significant increase in relapses of papulopustular rosacea during the pandemic. An appropriate anti-parasitic treatment may reduce the number of recurrences due to mask use.

摘要

引言

在新冠疫情期间,个人防护装备,尤其是口罩,成为参与各种活动的一项基本需求。几篇文章报道了与佩戴口罩相关的面部皮肤病(如痤疮、玫瑰痤疮)复发率上升。

目的

评估与佩戴口罩相关的玫瑰痤疮复发次数。

方法

本前瞻性研究针对疫情前被诊断为轻度和中度丘疹脓疱型玫瑰痤疮的成年患者开展。所有患者在2019年接受了为期4个月的局部伊维菌素治疗后,此前已实现部分或完全缓解。我们在两个不同阶段收集数据,这两个阶段的特点是疫情期间和疫情后口罩使用强度不同。我们通过对疾病的临床评估、关于个人习惯的问卷以及标准化的皮肤表面活检来收集数据,以研究蠕形螨计数。

结果

我们共纳入30名患者。在疫情期间,30名患者中有5名出现轻度丘疹脓疱型玫瑰痤疮复发;5名复发患者中有4名的蠕形螨样本呈阳性。在疫情后阶段,30名患者中有4名报告玫瑰痤疮复发(3名轻度,1名中度丘疹脓疱型)。在蠕形螨检查中,4名复发患者中有1名呈阳性。

结论

我们未发现疫情期间丘疹脓疱型玫瑰痤疮复发有显著增加。适当的抗寄生虫治疗可能会减少因佩戴口罩导致的复发次数。

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本文引用的文献

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Ocular manifestations of rosacea: A clinical review.酒渣鼻的眼部表现:临床综述。
Clin Exp Ophthalmol. 2021 Mar;49(2):104-117. doi: 10.1111/ceo.13900. Epub 2021 Feb 3.
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Rosacea and the Microbiome: A Systematic Review.酒渣鼻与微生物群:一项系统综述。
Dermatol Ther (Heidelb). 2021 Feb;11(1):1-12. doi: 10.1007/s13555-020-00460-1. Epub 2020 Nov 10.

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