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应用超声生物显微镜对皮质性年龄相关性白内障患者晶状体生物学参数的影像学分析。

Imaging analysis of the biological parameters of the lens in patients with cortical age-related cataracts using ultrasound biomicroscopy.

机构信息

Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao, China.

The Affiliated Hospital of Qingdao University, Qingdao, China.

出版信息

BMC Ophthalmol. 2023 Nov 22;23(1):480. doi: 10.1186/s12886-023-03227-2.

DOI:10.1186/s12886-023-03227-2
PMID:37993828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10666407/
Abstract

BACKGROUND

The spatial position of the lens in patients with cortical age-related cataract (CARC) is unclear. We investigated a basis for the assessment of visual quality after cataract surgery by analysing the ultrasound biomicroscopic characteristics of the biological parameters of the lens in patients with CARC.

METHODS

In this retrospective study, 119 patients (50 males and 69 females, totalling 238 eyes) with CARC who underwent simple cataract surgery were selected. The lens thickness (LT), axial length (AL), anterior chamber depth (ACD), lens vault (LV), trabecular-iris angle (TIA), iris-lens angle (ILA), iris-lens contact distance (ILCD) were measured by A-scan ultrasound and ultrasound biomicroscopy. The corresponding lens position (LP) and relative lens position (RLP) were calculated.

RESULTS

LP was greater in men than in women (P < 0.05), LV was smaller in men than in women (P = 0.002), ILA and ILCD were not statistically significant (P = 0.072 and P = 0.854, respectively). There were significant differences in TIA, ILA, and ILCD in the four quadrants (all P < 0.05), with a trend in the distribution of TIA: superior < inferior < nasal < temporal, ILA: nasal < inferior < temporal < superior, and ILCD: superior < temporal < inferior < nasal.

CONCLUSIONS

The lens protrudes more obviously in females than in males and the lens tilts to a certain extent with the increase of age and tends to be more upward and temporal in the supine position. Therefore, trends in lens-related parameters in patients with CARC should be taken seriously.

摘要

背景

皮质年龄相关性白内障(CARC)患者晶状体的空间位置尚不清楚。我们通过分析 CARC 患者晶状体生物学参数的超声生物显微镜特征,研究了评估白内障手术后视觉质量的基础。

方法

本回顾性研究纳入了 119 例(男 50 例,女 69 例,共 238 只眼)行单纯白内障手术的 CARC 患者。采用 A 型超声测量晶状体厚度(LT)、眼轴长度(AL)、前房深度(ACD)、晶状体拱高(LV)、小梁虹膜角(TIA)、虹膜晶状体角(ILA)、虹膜晶状体接触距离(ILCD)。计算相应的晶状体位置(LP)和相对晶状体位置(RLP)。

结果

男性 LP 大于女性(P<0.05),男性 LV 小于女性(P=0.002),ILA 和 ILCD 无统计学差异(P=0.072 和 P=0.854)。四个象限的 TIA、ILA 和 ILCD 差异均有统计学意义(均 P<0.05),TIA 呈上方<下方<鼻侧<颞侧分布趋势,ILA 呈鼻侧<下方<颞侧<上方分布趋势,ILCD 呈上方<颞侧<下方<鼻侧分布趋势。

结论

女性晶状体突出较男性明显,晶状体随年龄的增长有一定程度的倾斜,仰卧位时晶状体向上、颞侧倾斜的趋势更为明显。因此,应重视 CARC 患者晶状体相关参数的变化趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b35/10666407/dc0988b3af0d/12886_2023_3227_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b35/10666407/a19afb5d7d8c/12886_2023_3227_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b35/10666407/dc0988b3af0d/12886_2023_3227_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b35/10666407/a19afb5d7d8c/12886_2023_3227_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b35/10666407/dc0988b3af0d/12886_2023_3227_Figb_HTML.jpg

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