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白内障合并开角型青光眼患者眼前节光学相干断层扫描成像及眼生物测量。

Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity.

机构信息

Ophthalmology Department, Lithuanian University of Health Sciences, Eiveniu g. 2, 50161, Kaunas, Lithuania.

Biostatistician, Odontology faculty, Department of Dental and Oral Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania.

出版信息

BMC Ophthalmol. 2021 Mar 8;21(1):127. doi: 10.1186/s12886-021-01874-x.

DOI:10.1186/s12886-021-01874-x
PMID:33685443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7941888/
Abstract

BACKGROUND

Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glaucoma comorbidity.

MATERIALS AND METHODS

This prospective comparative case-control study included 62 subjects (38 with cataract only and 24 with cataract and glaucoma). A full ophthalmic examination including, Goldmann applanation tonometry, anterior chamber swept source optical coherence tomography (DRI OCT Triton plus (Ver.10.13)) and swept source optical biometry (IOL Master 700 v1.7) was performed on all participants.

RESULTS

We found that ocular biometry parameters and anterior chamber parameters were not significantly different among groups. However, when we added cut-off values for narrow angles, we found that glaucoma group tended to have more narrow angles than control group. IOP was higher in glaucoma group despite all glaucoma patients having medically controlled IOP. In all subjects, anterior chamber parameters correlated well with lens position (LP), but less with relative lens position, while LP cut-off value of 5.1 mm could be used for predicting narrow anterior chamber angle parameters.

CONCLUSIONS

Cataract patients tend to develop narrow anterior chamber angles. Anterior chamber angle parameters have a positive moderate to strong relationship with lens position. LP may be used predicting narrow angles.

摘要

背景

眼前房角度解剖结构从眼部生物测量学的角度来看可能是降低眼压（IOP）的关键因素，尤其是在青光眼患者中。我们旨在研究伴有或不伴有青光眼合并症的白内障患者术前的眼前房角度和生物测量数据。

材料和方法

这是一项前瞻性病例对照研究，共纳入 62 名受试者（38 名单纯白内障患者和 24 名白内障合并青光眼患者）。所有参与者均进行全面眼科检查，包括 Goldmann 压平眼压测量、前房扫频源光学相干断层扫描（DRI OCT Triton plus（Ver.10.13））和扫频源光学生物测量仪（IOL Master 700 v1.7）。

结果

我们发现各组之间的眼部生物测量参数和前房参数无显著差异。然而，当我们加入窄角的截止值时，我们发现青光眼组的窄角倾向比对照组多。尽管所有青光眼患者的眼压均得到药物控制，但青光眼组的眼压仍较高。在所有受试者中，前房参数与晶状体位置（LP）相关性良好，但与相对晶状体位置相关性较差，而 LP 截止值为 5.1mm 可用于预测窄前房角参数。

结论

白内障患者易发生窄眼前房角度。前房角度参数与晶状体位置呈正相关，相关性为中度至高度。LP 可用于预测窄角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/6fbc1e422455/12886_2021_1874_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/9ce14b1aafac/12886_2021_1874_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/1bef7b03c725/12886_2021_1874_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/9189182b63eb/12886_2021_1874_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/d1e7fb54d4c8/12886_2021_1874_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/6fbc1e422455/12886_2021_1874_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/9ce14b1aafac/12886_2021_1874_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/1bef7b03c725/12886_2021_1874_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/9189182b63eb/12886_2021_1874_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/d1e7fb54d4c8/12886_2021_1874_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2921/7941888/6fbc1e422455/12886_2021_1874_Fig5_HTML.jpg

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