Marcolini Federica, Ravaglia Alessandro, Tempia Valenta Silvia, Bosco Giovanna, Marconi Giorgia, Sanna Federica, Zilli Giulia, Magrini Enrico, Picone Flavia, De Ronchi Diana, Atti Anna Rita
Department of Biomedical and Neuromotor Sciences, University of Bologna, Viale Pepoli 5, 40123, Bologna, Italy.
Department of Clinical Nutrition, AUSL Bologna, Bologna, Italy.
J Eat Disord. 2023 Nov 22;11(1):208. doi: 10.1186/s40337-023-00925-6.
Anorexia Nervosa (AN) poses significant therapeutic challenges, especially in cases meeting the criteria for Severe and Enduring Anorexia Nervosa (SE-AN). This subset of AN is associated with severe medical complications, frequent use of services, and the highest mortality rate among psychiatric disorders.
In the present case series, 14 patients were selected from those currently or previously taken care of at the Eating Disorders Outpatients Unit of the Maggiore Hospital in Bologna between January 2012 and May 2023. This case series focuses on the effects of the disease, the treatment compliance, and the description of those variables that could help understand the great complexity of the disorder.
This case series highlights the relevant issue of resistance to treatment, as well as medical and psychological complications that mark the life course of SE-AN patients. The chronicity of these disorders is determined by the overlapping of the disorder's ego-syntonic nature, the health system's difficulty in recognizing the problem in its early stages, and the presence of occupational and social impairment.
神经性厌食症（AN）带来了重大的治疗挑战，尤其是在符合重度及持续性神经性厌食症（SE-AN）标准的病例中。AN的这一亚类与严重的医学并发症、频繁使用医疗服务以及精神疾病中最高的死亡率相关。
在本病例系列中，从2012年1月至2023年5月期间在博洛尼亚马焦雷医院饮食失调门诊接受当前或既往治疗的患者中选取了14例。本病例系列重点关注该疾病的影响、治疗依从性以及那些有助于理解该疾病复杂性的变量描述。
本病例系列突出了治疗抵抗这一相关问题，以及标志着SE-AN患者生命历程的医学和心理并发症。这些疾病的慢性化是由该疾病自我和谐的本质、卫生系统在早期阶段识别问题的困难以及职业和社会功能损害的存在共同导致的。
