Mungalsingh Melanie A, Thompson Benjamin, Peterson Sean D, Murphy Paul J
School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada.
Center for Eye and Vision Research, Hong Kong, China.
Ophthalmic Physiol Opt. 2024 Jan;44(1):32-41. doi: 10.1111/opo.13252. Epub 2023 Nov 23.
To identify the stimulus airflow characteristics and confirm the consistency of a novel air jet-based aesthesiometer capable of producing and applying multiple stimuli separated either by time and/or by space.
A novel aesthesiometer (Dolphin Aesthesiometer) was designed around a micro-blower under software management. Two nozzle attachments assisted in airflow control (flexible tube 1.6 mm diameter; brass tube 0.5 mm diameter). Four studies that tested the characteristics of the airflow and stimulus consistency were completed: (i) airflow pattern/trajectory, (ii) airflow surface dispersion, (iii) force of airflow across a range of stimulus strengths and (iv) thermal effects on the ocular surface.
Stimulus characteristic studies revealed: (i) airflow is coherent within the expected test distance range for the instrument, and spread rate is constant irrespective of stimulus strength; (ii) airflow dispersion occurs upon encountering a surface and dispersion increases with increasing airflow rate; (iii) a consistent and small force (10 N) is applied by the airflow and (iv) repeatable thermal effects occur in relation to the airflow, and the mode of stimulation of the Dolphin aesthesiometer is predominantly thermal in nature.
These studies confirm the repeatability and consistency of the novel instrument. The device is suitable for measuring corneal sensitivity. The availability of additional air jets allows the application of multiple stimuli to facilitate corneal summation investigations.
确定刺激气流特性,并确认一种新型基于喷气的麻醉仪的一致性,该麻醉仪能够产生并施加由时间和/或空间分隔的多种刺激。
围绕一台在软件管理下的微型吹风机设计了一种新型麻醉仪(海豚麻醉仪)。两种喷嘴附件有助于气流控制(直径1.6毫米的软管;直径0.5毫米的铜管)。完成了四项测试气流特性和刺激一致性的研究:(i)气流模式/轨迹,(ii)气流表面扩散,(iii)一系列刺激强度下的气流力,以及(iv)对眼表的热效应。
刺激特性研究表明:(i)在仪器预期的测试距离范围内气流是连贯的,且扩散速率与刺激强度无关,保持恒定;(ii)气流遇到表面时会发生扩散,且扩散随着气流速率的增加而增加;(iii)气流施加的力一致且较小(10 N),以及(iv)与气流相关的可重复热效应会发生,并且海豚麻醉仪的刺激模式本质上主要是热刺激。
这些研究证实了该新型仪器的可重复性和一致性。该设备适用于测量角膜敏感性。额外喷气装置的可用性允许施加多种刺激,以促进角膜总和研究。