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[丙型肝炎病毒感染继发膜增生性肾小球肾炎的管理]

[Management of membranoproliferative glomerulonephritis secondary to infection by hepatitis C virus].

作者信息

Lasierra Lavilla Ignacio, Perona Caro Amalia, Del Agua Arias-Camisón Celia, Caballero Castro Julien Paola

机构信息

Servicio Aragonés de Salud. Hospital. Hospital Obispo Polanco. Servicio de Medicina Interna. Teruel. España..

Servicio Aragonés de Salud. Hospital. Hospital Obispo Polanco. Servicio de Nefrología. Teruel. España..

出版信息

An Sist Sanit Navar. 2023 Nov 15;46(3):e1055. doi: 10.23938/ASSN.1055.

DOI:10.23938/ASSN.1055
PMID:37994841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10767695/
Abstract

Membranoproliferative glomerulonephritis is an uncommon condition that affects the glomeruli of the kidneys; its prevalence has decreased in our environment. Membranoproliferative glomerulonephritis has a characteristic histology that can be associated to different diseases. The clinical presentation varies, and to achieve a definitive diagnosis a renal biopsy must be done. Treatment is based on the underlying disease; when a drop in glomerular filtration rate is detected, immunosuppressants are prescribed. We describe the management of a 47-year-old female with membranoproliferative glomerulonephritis secondary to hepatitis C virus infection, a condition with very low prevalence.

摘要

膜增生性肾小球肾炎是一种影响肾脏肾小球的罕见病症；在我们所处的环境中其患病率已有所下降。膜增生性肾小球肾炎具有可与不同疾病相关联的特征性组织学表现。临床表现各异，要做出明确诊断必须进行肾活检。治疗基于潜在疾病；当检测到肾小球滤过率下降时，会开具免疫抑制剂。我们描述了一名47岁丙型肝炎病毒感染继发膜增生性肾小球肾炎女性患者的治疗情况，这种病症的患病率极低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666e/10767695/4a12a9bbd4a4/assn-46-03-e1055-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666e/10767695/32c59c891973/assn-46-03-e1055-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666e/10767695/4a12a9bbd4a4/assn-46-03-e1055-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666e/10767695/32c59c891973/assn-46-03-e1055-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/666e/10767695/4a12a9bbd4a4/assn-46-03-e1055-g2.jpg

相似文献

1
[Management of membranoproliferative glomerulonephritis secondary to infection by hepatitis C virus].[丙型肝炎病毒感染继发膜增生性肾小球肾炎的管理]
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本文引用的文献

1
KDIGO 2022 Clinical Practice Guideline FOR the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease.KDIGO 2022慢性肾脏病丙型肝炎预防、诊断、评估及治疗临床实践指南
Kidney Int. 2022 Dec;102(6S):S129-S205. doi: 10.1016/j.kint.2022.07.013.
2
KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases.KDIGO 2021肾小球疾病管理临床实践指南。
Kidney Int. 2021 Oct;100(4S):S1-S276. doi: 10.1016/j.kint.2021.05.021.
3
Hepatitis C-related membranoproliferative glomerulonephritis in the era of direct antiviral agents.
直接抗病毒药物时代的丙型肝炎相关膜增殖性肾小球肾炎。
J Bras Nefrol. 2022 Apr-Jun;44(2):291-295. doi: 10.1590/2175-8239-JBN-2020-0148.
4
Treatment for hepatitis C virus-associated mixed cryoglobulinaemia.丙型肝炎病毒相关混合性冷球蛋白血症的治疗
Cochrane Database Syst Rev. 2018 May 7;5(5):CD011403. doi: 10.1002/14651858.CD011403.pub2.
5
New classification of membranoproliferative glomerulonephritis: a good start but a long way to go.膜增生性肾小球肾炎的新分类：良好开端，但仍任重道远。
Kidney Res Clin Pract. 2014 Dec;33(4):171-3. doi: 10.1016/j.krcp.2014.10.005. Epub 2014 Nov 3.
6
Update on membranoproliferative GN.膜增生性 GN 的最新进展。
Clin J Am Soc Nephrol. 2014 Mar;9(3):600-8. doi: 10.2215/CJN.06410613. Epub 2014 Jan 9.
7
Membranoproliferative glomerulonephritis--a new look at an old entity.膜增生性肾小球肾炎——对一个旧有疾病的新认识。
N Engl J Med. 2012 Mar 22;366(12):1119-31. doi: 10.1056/NEJMra1108178.
8
Membranoproliferative glomerulonephritis secondary to monoclonal gammopathy.继发于单克隆丙种球蛋白病的膜增生性肾小球肾炎。
Clin J Am Soc Nephrol. 2010 May;5(5):770-82. doi: 10.2215/CJN.06760909. Epub 2010 Feb 25.
9
Characteristics of proliferative glomerulo-nephritis with monoclonal IgG deposits associated with membranoproliferative features.伴有膜增生性特征的单克隆IgG沉积的增殖性肾小球肾炎的特点
Clin Nephrol. 2009 Jul;72(1):46-54. doi: 10.5414/cnp72046.
10
Long-term effects of anti-CD20 monoclonal antibody treatment of cryoglobulinaemic glomerulonephritis.抗CD20单克隆抗体治疗冷球蛋白血症性肾小球肾炎的长期疗效
Nephrol Dial Transplant. 2004 Dec;19(12):3054-61. doi: 10.1093/ndt/gfh469. Epub 2004 Oct 19.