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妊娠期糖尿病筛查:通过一种几乎无味的葡萄糖聚合物进行一小时碳水化合物耐量试验。

Screening for gestational diabetes: one-hour carbohydrate tolerance test performed by a virtually tasteless polymer of glucose.

作者信息

Reece E A, Holford T, Tuck S, Bargar M, O'Connor T, Hobbins J C

出版信息

Am J Obstet Gynecol. 1987 Jan;156(1):132-4. doi: 10.1016/0002-9378(87)90223-7.

Abstract

Although the 1-hour 50 gm blood glucose screening test is an effective way of detecting diabetes in pregnancy, the taste of available glucose drinks often creates gastrointestinal symptoms and leads to refusal of the patient to be tested. The efficacy of a virtually tasteless glucose polymer in testing carbohydrate tolerance in pregnancy was determined. Sixty-one pregnant patients undergoing screening for gestational diabetes underwent a 1-hour carbohydrate tolerance test of both glucose and a glucose polymer within 3 days of each other. Analysis of the data revealed a high degree of agreement between the results of the 1-hour carbohydrate tolerance test (kappa = 0.62, p less than 0.0001). These data suggest that glucose polymer can be used effectively in screening for gestational diabetes.

摘要

尽管1小时50克血糖筛查试验是检测妊娠期糖尿病的有效方法,但现有葡萄糖饮料的味道常常会引发胃肠道症状,导致患者拒绝接受检测。研究确定了一种几乎无味的葡萄糖聚合物在检测妊娠期碳水化合物耐受性方面的效果。61名接受妊娠期糖尿病筛查的孕妇在彼此相隔3天内分别接受了葡萄糖和葡萄糖聚合物的1小时碳水化合物耐受性试验。数据分析显示,1小时碳水化合物耐受性试验结果之间具有高度一致性(kappa = 0.62,p小于0.0001)。这些数据表明,葡萄糖聚合物可有效用于妊娠期糖尿病的筛查。

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