Chao-Écija Alvaro, López-González Manuel Víctor, Dawid-Milner Marc Stefan
Autonomic Nervous System Unit, CIMES, School of Medicine, University of Málaga, 29071 Malaga, Spain.
Biomedical Research Institute of Málaga (IBIMA), 29590 Malaga, Spain.
Biology (Basel). 2023 Nov 16;12(11):1438. doi: 10.3390/biology12111438.
is a new R package designed for the complete evaluation of closed-loop cardiovascular interactions and baroreflex sensitivity estimated from continuous non-invasive heart rate and blood pressure recordings. In this work, we highlight the importance of this software tool in the context of human cardiovascular and autonomic neurophysiology. A summary of the main algorithms that uses are reviewed, and the workflow of this package is also discussed. We present the results obtained from this tool after its application in three clinical settings. These results support the potential clinical and scientific applications of this tool. The open-source tool can be downloaded from a public GitHub repository, as well as its specific application, . The open-source nature of the tool may benefit the future continuation of this work.
是一个新的R软件包，旨在对闭环心血管相互作用和根据连续无创心率和血压记录估计的压力反射敏感性进行全面评估。在这项工作中，我们强调了该软件工具在人类心血管和自主神经生理学背景下的重要性。回顾了其使用的主要算法的总结，并讨论了该软件包的工作流程。我们展示了该工具在三种临床环境中应用后获得的结果。这些结果支持了该工具潜在的临床和科学应用。这个开源工具可以从公共的GitHub代码库下载，以及它的特定应用程序， 。该工具的开源性质可能有利于这项工作的未来延续。
