Poeys-Carvalho Rafael M P, Gonzalez Alice G M
Departament of Bromatology, Federal Fluminense University, Niterói, Brazil.
Crit Rev Food Sci Nutr. 2025;65(5):936-946. doi: 10.1080/10408398.2023.2284858. Epub 2023 Nov 24.
Vegetables are crucial for a healthy human diet due to their abundance of essential macronutrients and micronutrients. However, there have been increased reports of antimicrobial-resistant isolated from vegetables. is a large group of Gram-negative bacteria that can act as commensals, intestinal pathogens, or opportunistic extraintestinal pathogens. Extraintestinal infections caused by are a clinical concern due to antimicrobial resistance (AMR). β-lactams have high efficacy against Gram-negative bacteria and low toxicity for eukaryotic cells. These antimicrobials are widely used in the treatment of extraintestinal infections. This review aimed to conduct a literature survey of the last five years (2018-2023) on the occurrence of β-lactam-resistant in vegetables. Research was carried out in PubMed, Web of Science, Scopus, ScienceDirect, and LILACS (Latin American and Caribbean Health Sciences Literature) databases. After a careful evaluation, thirty-seven articles were selected. β-lactam-resistant , including extended-spectrum β-lactamases (ESBLs)-producing, AmpC β-lactamases, and carbapenemases, have been isolated from a wide variety of vegetables. Vegetables are vectors of β-lactam-resistant , contributing to the dissemination of resistance mechanisms previously observed only in the hospital environment.
蔬菜因其富含必需的大量营养素和微量营养素，对人类健康饮食至关重要。然而，从蔬菜中分离出的耐抗菌药物的报告有所增加。大肠埃希菌是一大类革兰氏阴性菌，可作为共生菌、肠道病原体或机会性肠外病原体。大肠埃希菌引起的肠外感染因抗菌药物耐药性（AMR）而成为临床关注的问题。β-内酰胺类药物对革兰氏阴性菌疗效高，对真核细胞毒性低。这些抗菌药物广泛用于治疗大肠埃希菌肠外感染。本综述旨在对过去五年（2018 - 2023年）关于蔬菜中耐β-内酰胺类大肠埃希菌的发生情况进行文献调查。研究在PubMed、科学网、Scopus、ScienceDirect和LILACS（拉丁美洲和加勒比卫生科学文献）数据库中进行。经过仔细评估，选择了37篇文章。耐β-内酰胺类大肠埃希菌，包括产超广谱β-内酰胺酶（ESBLs）、AmpCβ-内酰胺酶和碳青霉烯酶的菌株，已从多种蔬菜中分离出来。蔬菜是耐β-内酰胺类大肠埃希菌的载体，促成了以前仅在医院环境中观察到的耐药机制的传播。
