Miyamura K, Kanzaki Y, Nagata M, Ishikawa T
Ann Allergy. 1987 Jan;58(1):36-40.
Nystagmus, head-deviation, and hearing loss were provoked by Type I allergy induced in guinea pigs with passive sensitization and specific antigen challenge. Mast cell degranulation, edema of connective tissue of the endolymphatic sac and endolymphatic hydrops were histologically observed. These findings indicated that Type I allergy can be induced in the inner ear, and that symptoms analogous to Meniere's disease may be induced by this response.
通过被动致敏和特异性抗原激发在豚鼠中诱导Ⅰ型过敏反应，引发了眼球震颤、头部偏斜和听力损失。组织学观察到肥大细胞脱颗粒、内淋巴囊结缔组织水肿和内淋巴积水。这些发现表明内耳可诱导Ⅰ型过敏反应，且这种反应可能诱发类似于梅尼埃病的症状。
