Department of Nutrition, Hospital Sírio Libanês, 91, Dona Adma Jafet, Street, São Paulo, 01308-901, SP, Brazil.
BMC Infect Dis. 2023 Nov 24;23(1):826. doi: 10.1186/s12879-023-08833-5.
INTRODUCTION: Severe forms of COVID-19 are more common in patients with abnormal fat distribution, particularly high visceral adiposity. The patient's muscle strength may be reduced during the acute phase of the infection. Electrical bioimpedance (BIA) is a non-invasive method for measuring body compartments and estimating visceral fat area (VFA) that can be used at the bedside. OBJECTIVE: To assess the association between several body composition parameters, primarily high adipose tissue and high VFA, in patients with and without a diagnosis of COVID-19 infection, and whether it worsened the severity parameters. METHODS: This retrospective cohort study was conducted in a private hospital in the city of São Paulo from March 2020 to August 2021. The demographic and clinical data was collected from medical reports. Body composition is assessed using the InBODY® model S10 bioelectrical impedance device and a Jamar® digital hydraulic manual dynamometer with a scale from 0 to 90 kg is used to measure handgrip strength (HGS). RESULTS: A total of 96 patients with a mean age of 69.1 years (SD 15) were divided into two groups of 48 individuals, with and without COVID-19 infection. Body mass index (odds ratio [OR]: 4.47, 95% confidence interval [CI]: 1.69, 11.83), fat mass (OR: 2.03, 95% CI: 0.48, 8.55), and VFA (OR: 1.08, 95% CI: 0.33, 3.53) were all higher in the infection group. When COVID-19 patients were evaluated, those with higher VFA had longer hospital stays (OR: 0.99, 95% CI: 0.97, 1.01) and used more vasoactive drugs (p = 0.043). Patients with COVID-19 with poor handgrip strength were 3.29 times more likely to require a prolonged intensive care unit (ICU) stay. CONCLUSION: The study concluded that excess weight and body fat are significantly associated with COVID-19 involvement, but the severity is primarily related to a greater area of visceral fat. The use of bioimpedance for visceral fat measurement was effective, as it is a simple method performed in the hospital setting that does not require the use of radiation.
简介：COVID-19 的严重形式在脂肪分布异常的患者中更为常见，尤其是内脏脂肪过多。患者的肌肉力量可能会在感染的急性期减弱。生物电阻抗（BIA）是一种测量身体成分并估计内脏脂肪面积（VFA）的非侵入性方法，可在床边使用。 目的：评估患有和未患有 COVID-19 感染的患者之间几种身体成分参数（主要是高脂肪组织和高 VFA）之间的关联，以及这些参数是否会使严重程度参数恶化。 方法：这是一项在 2020 年 3 月至 2021 年 8 月期间在圣保罗市的一家私人医院进行的回顾性队列研究。从病历中收集人口统计学和临床数据。使用 InBODY® S10 生物电阻抗设备评估身体成分，使用 Jamar® 数字液压手动测力计（范围为 0 至 90 公斤）测量握力（HGS）。 结果：共有 96 名平均年龄为 69.1 岁（SD 15）的患者分为两组，每组 48 人，一组有 COVID-19 感染，一组没有。身体质量指数（比值比 [OR]：4.47，95%置信区间 [CI]：1.69，11.83）、脂肪量（OR：2.03，95% CI：0.48，8.55）和 VFA（OR：1.08，95% CI：0.33，3.53）在感染组中均较高。当评估 COVID-19 患者时，那些 VFA 较高的患者住院时间更长（OR：0.99，95% CI：0.97，1.01），并且使用更多的血管活性药物（p=0.043）。COVID-19 患者握力差的患者需要长时间入住重症监护病房（ICU）的可能性增加 3.29 倍。 结论：研究得出的结论是，超重和体脂与 COVID-19 的发生显著相关，但严重程度主要与更大的内脏脂肪面积有关。生物电阻抗法用于测量内脏脂肪是有效的，因为它是一种简单的方法，可在医院环境中进行，无需使用辐射。
Int J Colorectal Dis. 2021-11
Rocz Panstw Zakl Hig. 2024-8-14
J Diabetes Complications. 2016-3
Diagn Interv Radiol. 2010-2-18
Front Endocrinol (Lausanne). 2024
Aging Clin Exp Res. 2021-10
Front Endocrinol (Lausanne). 2021-4-30
JPEN J Parenter Enteral Nutr. 2021-8
Zotero 插件