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通过构建金刚烷骨架合成1,2-二取代金刚烷衍生物

Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework.

作者信息

Todd Matthew, Hrdina Radim

机构信息

Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 12043 Praha, Czech Republic.

出版信息

Molecules. 2023 Nov 16;28(22):7636. doi: 10.3390/molecules28227636.

DOI:10.3390/molecules28227636
PMID:38005358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10675813/
Abstract

This review summarizes achievements in the synthesis of 1,2-disubstituted adamantane derivatives by the construction of the tricyclic framework either by total synthesis or by ring expansion/contraction reactions of corresponding adamantane homologues. It is intended to complement reviews focusing on the preparation of 1,2-disubstituted derivatives by C-H functionalization methods.

摘要

本综述总结了通过全合成或相应金刚烷同系物的扩环/缩环反应构建三环骨架来合成1,2-二取代金刚烷衍生物的研究成果。其目的是补充侧重于通过C-H官能化方法制备1,2-二取代衍生物的综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6896/10675813/0e64fc46b7ff/molecules-28-07636-sch018.jpg
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本文引用的文献

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Adamantane Annulation to Arenes: A Strategy for Property Modulation of Aromatic π-Systems.金刚烷环化芳构化：调节芳环π体系性质的策略。
J Am Chem Soc. 2023 May 31;145(21):11754-11763. doi: 10.1021/jacs.3c02788. Epub 2023 May 19.
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RSC Adv. 2022 Oct 31;12(48):31056-31060. doi: 10.1039/d2ra06402b. eCollection 2022 Oct 27.
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Chiral Motifs in Highly Interpenetrated Metal-Organic Frameworks Formed from Achiral Tetrahedral Ligands.
由非手性四面体配体形成的高度互穿金属有机框架中的手性基序
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Direct radical functionalization methods to access substituted adamantanes and diamondoids.直接自由基官能化方法构建取代的金刚烷和类金刚石。
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Self-Assembly and Circularly Polarized Luminescence from Achiral Pyrene-Adamantane Conjugates by Selective Inclusion with Cyclodextrins.手性芘-金刚烷衍生物通过环糊精的选择性包合实现自组装及圆偏振发光
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