Shi Yaoyao, Sheng Wei, Fu Yangyang, Liu Youwen
College of Physics, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China.
College of Astronautics, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China.
Nat Commun. 2023 Nov 25;14(1):7742. doi: 10.1038/s41467-023-43674-5.
Optical imaging in scattering media is important to many fields but remains challenging. Recent methods have focused on imaging through thin scattering layers or thicker scattering media with prior knowledge of the sample, but this still limits practical applications. Here, we report an imaging method named 'speckle kinetography' that enables high-resolution imaging in unknown scattering media with thicknesses up to about 6 transport mean free paths. Speckle kinetography non-invasively records a series of incoherent speckle images accompanied by object motion and the inherently retained object information is extracted through an overlapping speckle correlation algorithm to construct the object's autocorrelation for imaging. Under single-colour light-emitting diode, white light, and fluorescence illumination, we experimentally demonstrate 1 μm resolution imaging and tracking of objects moving in scattering samples, while reducing the requirements for prior knowledge. We anticipate this method will enable imaging in currently inaccessible scenarios.
散射介质中的光学成像对许多领域都很重要，但仍然具有挑战性。最近的方法主要集中在通过薄散射层或具有样品先验知识的较厚散射介质进行成像，但这仍然限制了实际应用。在这里，我们报告了一种名为“散斑动态成像”的成像方法，该方法能够在厚度达约6个输运平均自由程的未知散射介质中进行高分辨率成像。散斑动态成像通过非侵入性记录一系列伴随着物体运动的非相干散斑图像，并通过重叠散斑相关算法提取固有保留的物体信息，以构建物体的自相关用于成像。在单色发光二极管、白光和荧光照明下，我们通过实验证明了在散射样品中对移动物体进行1μm分辨率的成像和跟踪，同时降低了对先验知识的要求。我们预计这种方法将能够在目前无法实现的场景中进行成像。
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