通过圆二色性对血液疾病进行表征。
Characterization of haem disorder by circular dichroism.
作者信息
Aojula H S, Wilson M T, Drake A
出版信息
Biochem J. 1986 Jul 15;237(2):613-6. doi: 10.1042/bj2370613.
Abstract
Native and reconstituted myoglobin were prepared and their c.d. spectra recorded in the Soret region. Time-dependent changes in dichroism following reconstitution were observed and related to haem orientational disorder. Comparative c.d. studies, in agreement with n.m.r. studies, reveal that the degree and nature of this disorder are species-dependent.
摘要
制备了天然肌红蛋白和重组肌红蛋白，并记录了它们在索雷特区域的圆二色光谱。观察到重组后二色性随时间的变化，并将其与血红素取向紊乱相关联。与核磁共振研究一致的比较性圆二色研究表明，这种紊乱的程度和性质因物种而异。
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