重组人血红蛋白中的血液疾病。
Haem disorder in reconstituted human haemoglobin.
作者信息
Docherty J C, Brown S B
出版信息
Biochem J. 1982 Dec 1;207(3):583-7. doi: 10.1042/bj2070583.
Abstract
Degradation of the haem of haemoglobin (used as a chemical probe of the haem-protein relationship), suggests that reconstituted human haemoglobin contains significant haem disorder. This results from the insertion of haem into globin with an orientation 180 degrees different from the natural orientation. Haem disorder also slowly occurs in methaemoglobin solutions.
摘要
血红蛋白血红素的降解（用作血红素-蛋白质关系的化学探针）表明，重组人血红蛋白存在明显的血红素紊乱。这是由于血红素以与自然方向相差180度的方向插入珠蛋白中所致。高铁血红蛋白溶液中也会缓慢出现血红素紊乱。
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