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山羊乳腺中三酰甘油合成的单酰甘油途径缺失。

Absence of monoacylglycerol pathway for triacylglycerol synthesis in goat mammary gland.

作者信息

Hansen H O, Jensen S S, Knudsen J

出版信息

Biochem J. 1986 Aug 15;238(1):173-6. doi: 10.1042/bj2380173.

DOI:10.1042/bj2380173
PMID:3800931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1147112/
Abstract

Both subcellular fractions of lactating goat mammary gland and dispersed lactating goat mammary-gland cells were able to incorporate [U-3H]2-O-hexadecylglycerol into monoalkyl-monoacylglycerol. However, the incorporation of [U-3H]2-O-hexadecylglycerol into monoalkyl-monoacylglycerol by dispersed cells was not accompanied by incorporation of fatty acid synthesized de novo or added radiolabelled fatty acid. The result therefore shows that an active monoacylglycerol pathway does not exist in goat mammary gland.

摘要

泌乳山羊乳腺的两个亚细胞部分以及分散的泌乳山羊乳腺细胞都能够将[U-3H]2-O-十六烷基甘油掺入单烷基单酰基甘油中。然而,分散细胞将[U-3H]2-O-十六烷基甘油掺入单烷基单酰基甘油的过程中,并没有伴随着从头合成的脂肪酸或添加的放射性标记脂肪酸的掺入。因此,结果表明山羊乳腺中不存在活跃的单酰基甘油途径。

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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
INCORPORATION OF SHORT- AND LONG-CHAIN FATTY ACIDS INTO GLYCERIDES BY LACTATING-GOAT MAMMARY TISSUE.泌乳山羊乳腺组织将短链和长链脂肪酸掺入甘油酯的过程。
Biochim Biophys Acta. 1964 Jun 15;84:251-63. doi: 10.1016/0926-6542(64)90054-x.
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Acceptors of fatty acid for glyceride synthesis in guinea pig mammary gland.豚鼠乳腺中用于甘油酯合成的脂肪酸受体。
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Utilization of neutral glycerides and phosphatidylethanolamine by the phospholipase A-1 of the plasma membranes of rat liver.大鼠肝脏质膜磷脂酶A-1对中性甘油酯和磷脂酰乙醇胺的利用
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Palmitic acid and initiation of mammary glyceride synthesis via phosphatidic acid.棕榈酸与通过磷脂酸启动乳腺甘油酯合成
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Fatty acid synthetase from cow mammary gland tissue cells.来自奶牛乳腺组织细胞的脂肪酸合成酶。
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Biosynthesis of triglycerides in freshly secreted milk from goats.
Lipids. 1974 Nov;9(11):876-82. doi: 10.1007/BF02532613.
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Studies on the substrate specificity of the phospholipase A1 of the plasma membrane of rat liver.大鼠肝细胞膜磷脂酶A1的底物特异性研究。
J Biol Chem. 1974 Oct 25;249(20):6401-5.
9
Synthesis of milk specific fatty acids and proteins by dispersed goat mammary-gland epithelial cells.分散的山羊乳腺上皮细胞合成乳特异性脂肪酸和蛋白质。
Biochem J. 1986 Aug 15;238(1):167-72. doi: 10.1042/bj2380167.