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[肾小球疾病的流行病学:来自三级中心的报告]

[Epidemiology of glomerular disease: report from a third-level center].

作者信息

Martínez-Abadía Alejandra Itzel, Juárez-Sánchez José Óscar

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Nefrología. León, Guanajuato, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2023 Sep 18;61(Suppl 2):S185-S192.

PMID:38011679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10773916/
Abstract

BACKGROUND

Renal biopsy has become one of the pillars of nephrology practice, being a very important tool in the diagnostic approach of any nephrology center, since it contributes to the identification and adequate management of glomerular diseases, which represent the third cause of chronic kidney disease in the world. In Mexico there are few reports on the epidemiology of glomerular diseases; therefore, it is important to carry out this type of study.

OBJECTIVE

To identify which are the main glomerulopathies reported in our center, Determine the most prevalent glomerular syndrome according to the reported glomerulopathy, and identify the main complications after percutaneous renal biopsy.

MATERIAL AND METHODS

A retrolective cross-sectional study which included patients who underwent percutaneous biopsy of the native kidney from August 2020 to August 2022; we obtained information from the service's database.

RESULTS

89 biopsy reports were analyzed, out of which 66.29% corresponded to the female gender and 32.70% to the male gender. The average age was 37.6 ± 12.86 years. The most frequent primary glomerulopathy was focal segmental glomerulosclerosis (FSG) in 22.5%, followed by membranous nephropathy in 7.9%. The most frequent secondary glomerulopathy was lupus nephropathy in 42.7%. Nephrotic syndrome occurred in 43.85% of cases. 89% of the patients did not present post-biopsy complications.

CONCLUSIONS

FSG is the most common primary glomerulopathy. Nephrotic syndrome was the main indication for renal biopsy. The vast majority of patients did not present complications, so we can consider it to be a safe and above all useful procedure for the diagnosis of glomerular diseases.

摘要

背景

肾活检已成为肾脏病学实践的支柱之一,是任何肾脏病中心诊断方法中非常重要的工具,因为它有助于识别和妥善管理肾小球疾病,而肾小球疾病是全球慢性肾脏病的第三大病因。在墨西哥,关于肾小球疾病流行病学的报道很少;因此,开展此类研究很重要。

目的

确定我们中心报告的主要肾小球病,根据报告的肾小球病确定最常见的肾小球综合征,并确定经皮肾活检后的主要并发症。

材料与方法

一项回顾性横断面研究,纳入2020年8月至2022年8月接受经皮肾活检的患者;我们从该科室的数据库中获取信息。

结果

分析了89份活检报告,其中66.29%为女性,32.70%为男性。平均年龄为37.6±12.86岁。最常见的原发性肾小球病是局灶节段性肾小球硬化(FSG),占22.5%,其次是膜性肾病,占7.9%。最常见的继发性肾小球病是狼疮性肾炎,占42.7%。43.85%的病例出现肾病综合征。89%的患者未出现活检后并发症。

结论

FSG是最常见的原发性肾小球病。肾病综合征是肾活检的主要指征。绝大多数患者未出现并发症,因此我们可以认为它是一种安全且最重要的是对诊断肾小球疾病有用的方法。

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2
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本文引用的文献

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The spectrum of biopsy-proven glomerular diseases in a tertiary Hospital in Southern Brazil.巴西南部一家三级医院经活检证实的肾小球疾病谱。
BMC Nephrol. 2021 Dec 13;22(1):414. doi: 10.1186/s12882-021-02603-8.
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Spanish Registry of glomerulonephritis 2020 revisited: past, current data and new challenges.2020年西班牙肾小球肾炎登记回顾:过去、当前数据及新挑战
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Spectrum of biopsy proven renal diseases in Central China: a 10-year retrospective study based on 34,630 cases.华中地区经活检证实的肾脏疾病谱:一项基于 34630 例病例的 10 年回顾性研究。
Sci Rep. 2020 Jul 3;10(1):10994. doi: 10.1038/s41598-020-67910-w.
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Clinicopathologic correlations of renal biopsy findings from northeast China: A 10-year retrospective study.中国东北地区肾活检结果的临床病理相关性:一项10年回顾性研究。
Medicine (Baltimore). 2019 Jun;98(23):e15880. doi: 10.1097/MD.0000000000015880.
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[Economic impact of the chronic kidney disease: Perspective of the Instituto Mexicano del Seguro Social].[慢性肾脏病的经济影响:墨西哥社会保障局视角]
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Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry-publication on behalf of Taiwan Society of Nephrology.台湾地区肾小球疾病的分布:国家肾脏活检登记处初步报告——代表台湾肾脏病学会发表
BMC Nephrol. 2018 Jan 10;19(1):6. doi: 10.1186/s12882-017-0810-4.
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Patterns of renal disease in South Korea: a 20-year review of a single-center renal biopsy database.韩国的肾脏疾病模式:对单一中心肾脏活检数据库的20年回顾
Ren Fail. 2017 Nov;39(1):540-546. doi: 10.1080/0886022X.2017.1348955.
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Clinicopathologic correlations of renal pathology in the adult population of Poland.波兰成年人群肾脏病理学的临床病理相关性
Nephrol Dial Transplant. 2017 Apr 1;32(suppl_2):ii209-ii218. doi: 10.1093/ndt/gfw365.
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