Department of Medical Laboratory Science, Haematology Unit, Faculty of Basic Medical and Health Sciences, Thomas Adewumi University, Oko, Nigeria.
Department of Medical Biochemistry and Pharmacology, Faculty of Pure and Applied Sciences, Kwara State University, Malete, Nigeria.
Medicine (Baltimore). 2023 Nov 24;102(47):e36342. doi: 10.1097/MD.0000000000036342.
Erythrocyte antigens, particularly those which give rise to different blood group systems, are potentially known to perform as receptor sites for different types of disease-causing agents. It is for this reason that this study was carried out to determine the distribution of different blood groups and how susceptible they are to human immunodeficiency virus (HIV) infection. For this study, data were retrieved from different blood bank registers at 4 major blood banks in Ekiti State (National Blood Transfusion Services, Ado, State Specialist Hospital, Ikole, State Specialist Hospital, Ijero, State Specialist Hospital, Ikere. All in Ekiti State). Demographic data such as age and gender were collected on 2388 individuals who were recruited at the above stated facilities over a 2-year period. Their blood groups (Rhesus and ABO) and HIV status were equally recorded. Results of the ABO blood group analysis of the subjects showed that Blood Group O had the highest population (78.2%) while blood Group AB had the lowest (0.9%). The percentages of Rhesus positive and negative persons observed in this population were 94.7% and 5.3%, respectively. The total sero-prevalence of HIV infection was 0.81%. However, there was no significant difference in the prevalence of HIV among the different ABO and Rhesus blood types. This study revealed no association between ABO and Rhesus blood groups and HIV infection.
红细胞抗原,尤其是那些导致不同血型系统的抗原,已知可能作为不同类型致病因子的受体。正是出于这个原因,进行了这项研究,以确定不同血型的分布以及它们对人类免疫缺陷病毒 (HIV) 感染的易感性。在这项研究中,从埃基蒂州 4 家主要血库的不同血库登记处检索了数据(国家输血服务处、阿多州立专科医院、伊科勒州立专科医院、伊杰罗州立专科医院和伊克雷州立专科医院)。在上述设施中招募了 2388 名个体,收集了年龄和性别等人口统计学数据。同样记录了他们的血型(Rh 血型和 ABO 血型)和 HIV 状况。对受试者 ABO 血型分析的结果表明,血型 O 的人群最多(78.2%),而血型 AB 的人群最少(0.9%)。在该人群中观察到 Rh 阳性和阴性的比例分别为 94.7%和 5.3%。HIV 感染的总血清流行率为 0.81%。然而,不同 ABO 和 Rh 血型之间 HIV 的流行率没有显著差异。这项研究表明,ABO 和 Rh 血型与 HIV 感染之间没有关联。