ANAPP3对豚鼠隐动脉兴奋性接头电位的抑制作用。
Inhibition of the excitatory junction potential in the guinea-pig saphenous artery by ANAPP3.
作者信息
Cheung D W, Fujioka M
出版信息
Br J Pharmacol. 1986 Sep;89(1):3-5. doi: 10.1111/j.1476-5381.1986.tb11114.x.
Abstract
Electrical stimulation of the perivascular nerves of the guinea-pig saphenous artery elicited excitatory junction potentials (e.j.ps) in the smooth muscle cells. These e.j.ps were inhibited by arylazido aminopropionyl adenosine triphosphate (ANAPP3), a specific antagonist for the P2-purinoceptor, suggesting that ATP may be the neurotransmitter.
摘要
对豚鼠隐动脉血管周围神经进行电刺激，可在平滑肌细胞中诱发兴奋性接头电位（e.j.ps）。这些e.j.ps被芳基叠氮氨基丙酰三磷酸腺苷（ANAPP3）抑制，ANAPP3是P2嘌呤受体的特异性拮抗剂，这表明ATP可能是神经递质。
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