National Innovation Foundation (NIF), India, Grambharti, Amrapur, Gandhinagar, Mahudi Road, Gandhinagar, Gujarat, India.
Forensic Anthropology-1, Department of Forensic Medicine, YMC, Yenepoya Deemed to be University, University Road, Deralakatte, Mangaluru, Karnataka, 575018, India.
Curr Rheumatol Rev. 2024;20(3):241-269. doi: 10.2174/0115733971268416231116184056.
Arthritis is a medical condition that affects the joints and causes inflammation, pain, and stiffness. There are different types of arthritis, and it can affect people of all ages, even infants and the elderly. Recent studies have found that individuals with diabetes, heart disease, and obesity are more likely to experience arthritis symptoms. According to the World Health Organization, over 21% of people worldwide suffer from musculoskeletal problems. Roughly 42.19 million individuals in India, constituting around 0.31% of the populace, have been documented as having Rheumatic Arthritis (RA). Compared to other common diseases like diabetes, cancer, and AIDS, arthritis is more prevalent in the general population. Unfortunately, there is no specific cure for arthritis, and treatment plans usually involve non-pharmacological methods, surgeries, and medications that target specific symptoms. Plant-based remedies have also been shown to be effective in managing inflammation and related complications. In addition to therapies, maintaining a healthy diet, exercise, and weight management are essential for managing arthritis. This review discusses the causes, prevalence, diagnostic methods, current and prospective future treatments, and potential medicinal plants that may act as anti-inflammatory or anti-rheumatic agents. However, more research is necessary to identify the underlying mechanisms and active molecules that could improve arthritis treatment.
关节炎是一种影响关节并导致炎症、疼痛和僵硬的医学病症。有不同类型的关节炎,它可以影响所有年龄段的人,甚至婴儿和老年人。最近的研究发现,糖尿病、心脏病和肥胖症患者更有可能出现关节炎症状。根据世界卫生组织的数据,全球超过 21%的人患有肌肉骨骼问题。在印度,大约有 421.9 万人被记录为患有类风湿关节炎(RA),占总人口的 0.31%。与糖尿病、癌症和艾滋病等其他常见疾病相比,关节炎在普通人群中更为普遍。不幸的是,目前尚无针对关节炎的特定疗法,治疗方案通常包括非药物治疗、手术和针对特定症状的药物治疗。植物性疗法也已被证明可有效治疗炎症及相关并发症。除了治疗方法外,保持健康的饮食、运动和体重管理对于关节炎的管理也非常重要。本综述讨论了关节炎的病因、流行率、诊断方法、当前和未来的治疗方法,以及可能作为抗炎或抗风湿剂的药用植物。然而,需要更多的研究来确定潜在的机制和有效分子,以改善关节炎的治疗效果。