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髋部骨折后肌肉质量和力量的丧失:营养补充的干预目标。

Loss of Muscle Mass and Strength After Hip Fracture: an Intervention Target for Nutrition Supplementation.

机构信息

Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway Street, Room 648, Baltimore, MD, 21205, USA.

Mend Labs, New York, NY, USA.

出版信息

Curr Osteoporos Rep. 2023 Dec;21(6):710-718. doi: 10.1007/s11914-023-00836-0. Epub 2023 Nov 29.

Abstract

PURPOSEOF REVIEW

To summarize what is known about the deleterious effect of hip fracture on muscle mass and strength as well as the scientific evidence for post-surgical nutrition supplementation to maintain muscle and improve function.

RECENT FINDINGS

This review provides a discussion of the relationship between muscle mass, strength, and physical function following hip fracture, briefly describes the approaches to measuring lean mass, discusses prevalence of sarcopenia and malnutrition among older men and women with hip fracture, and reviews the effects of essential amino acids on muscle. Loss of muscle mass and strength following hip fracture is substantial with consequences for recovery of functional independence. EAA-based nutrition supplementation, which directly effects muscle, has potential to improve outcomes.

摘要

目的综述

总结髋部骨折对肌肉质量和力量的有害影响,以及术后营养补充以维持肌肉和改善功能的科学证据。

最新发现

本综述讨论了髋部骨折后肌肉质量、力量和身体功能之间的关系,简要描述了测量瘦体重的方法,讨论了老年髋部骨折男女患者中肌少症和营养不良的流行情况,并回顾了必需氨基酸对肌肉的影响。髋部骨折后肌肉质量和力量的大量损失对恢复功能独立性有影响。基于必需氨基酸的营养补充直接影响肌肉,具有改善结果的潜力。

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