Department of General Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Department of Orthopedic Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
J Appl Gerontol. 2021 Dec;40(12):1903-1913. doi: 10.1177/07334648211006519. Epub 2021 Apr 17.
Hip fracture is a serious clinical event with high morbidity and mortality. Sarcopenia is characterized by age-related loss of muscle mass and function, leading to several adverse health outcomes. In this systematic review, no limitation criteria were used for study selection and 327 studies were identified in the initial search. Of these, 11 studies comprising a total of 2,314 patients were selected. The overall proportion of older adults with hip fracture having sarcopenia was 44%, with a disparity of approximately 10% between men and women. Most studies have indicated that older adults with sarcopenia had poorer postoperative functional recovery than those without sarcopenia; the association between sarcopenia and high postoperative mortality or long hospital stay was heterogeneous. Well-organized studies with longer follow-up periods are warranted.
髋部骨折是一种严重的临床事件，具有较高的发病率和死亡率。肌少症的特征是与年龄相关的肌肉质量和功能丧失，导致多种不良健康后果。在本次系统评价中，未对研究选择设置任何限制标准，在最初的搜索中确定了 327 项研究。其中，有 11 项研究共纳入了 2314 名患者。髋部骨折的老年患者中肌少症的总体比例为 44%，男性和女性之间的差异约为 10%。大多数研究表明，患有肌少症的老年患者术后功能恢复较无肌少症患者差；肌少症与高术后死亡率或长住院时间之间的关联存在异质性。需要进行组织良好、随访时间更长的研究。
