Nilchian Firouzeh, Mosayebi Neda, Tarrahi Mohammad Javad, Pasyar Hamidreza
Department of Oral Public Health, Dental Materials Research Center, Dental Research Institute, School of Dentistry, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Orthodontics, Dental Research Center, School of Dentistry, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Dent Res J (Isfahan). 2023 Oct 26;20:104. eCollection 2023.
The aim of the present study was to compare dental indexes of pediatric Down syndrome (DS) patients to those who are healthy.
This study was carried out based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement guidelines. The researchers searched title and abstract of major databases, including ProQuest (ProQuest Dissertations and Theses Full Text: Health and Medicine, ProQuest Nursing and Allie Health Source), PubMed, Google Scholar, clinical key, up to date, springer, Cochrane, Scopus, Embase, and Web of Science (ISI), up to September 2020 with restriction to English and Persian language This meta-analysis study had three outcomes: decay/miss/filled index, plaque index, and gingival index. Effect size, including mean difference and its 95% of confidence interval, was calculated. The Newcastle-Ottawa Scale measured the quality of the selected studies. Heterogeneity was performed using the test and index, and reporting bias was assessed using a funnel plot and Egger and Begg's tests.
Fifteen studies conducted were included in the meta-analysis process.
It showed that DS patients had a higher plaque index and gingival index than healthy individuals, which means that the oral health status of these patients is worse and needs more attention.
本研究旨在比较小儿唐氏综合征（DS）患者与健康儿童的牙齿指数。
本研究依据系统评价和Meta分析的首选报告项目声明指南开展。研究人员检索了主要数据库的标题和摘要，包括ProQuest（ProQuest学位论文全文数据库：健康与医学、ProQuest护理与联合健康资源库）、PubMed、谷歌学术、临床关键数据库、最新数据库、施普林格、考科蓝、Scopus、Embase和科学网（ISI），检索截至2020年9月，限定语言为英语和波斯语。这项Meta分析研究有三个结果：龋失补指数、菌斑指数和牙龈指数。计算效应量，包括平均差及其95%置信区间。采用纽卡斯尔-渥太华量表评估所选研究的质量。使用 检验和 指数进行异质性分析，并通过漏斗图以及Egger和Begg检验评估报告偏倚。
纳入Meta分析过程的有15项已开展的研究。
结果显示，DS患者的菌斑指数和牙龈指数高于健康个体，这意味着这些患者的口腔健康状况较差，需要更多关注。
