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一种多模式抗菌药物管理干预措施，以改善新冠肺炎患者的抗生素处方开具情况。

A multimodal antimicrobial stewardship intervention to improve antibiotic prescribing in patients with COVID-19.

作者信息

Anderson Shaylee, Bennett Nicholas, Aragon Laura, Kennedy Kevin, Boyd Sarah

机构信息

University of Utah, Salt Lake City, UT, USA.

Saint Luke's Health System, Kansas City, MO, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2023 Oct 19;3(1):e172. doi: 10.1017/ash.2023.462. eCollection 2023.

DOI:10.1017/ash.2023.462
PMID:38028892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10644171/
Abstract

This study assessed outcomes prior to and after electronic medical record-based clinical decision support implementation combined with prospective audit in patients with COVID-19. This multimodal stewardship intervention was associated with a decrease in antibiotic exposure for patients with COVID-19 (44.4% vs 61.8%, = 0.002) within the first 7 days of hospitalization.

摘要

本研究评估了基于电子病历的临床决策支持系统结合前瞻性审核在新冠肺炎患者中实施前后的结果。这种多模式管理干预与新冠肺炎患者住院前7天内抗生素暴露的减少相关（44.4%对61.8%，P = 0.002）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8a1/10644171/af180eb881a3/S2732494X2300462X_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8a1/10644171/af180eb881a3/S2732494X2300462X_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8a1/10644171/af180eb881a3/S2732494X2300462X_fig1.jpg

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BMC Infect Dis. 2021 Jun 2;21(1):516. doi: 10.1186/s12879-021-06219-z.
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Empiric Antibacterial Therapy and Community-onset Bacterial Coinfection in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19): A Multi-hospital Cohort Study.2019冠状病毒病（COVID-19）住院患者的经验性抗菌治疗与社区获得性细菌合并感染：一项多中心队列研究
Clin Infect Dis. 2021 May 18;72(10):e533-e541. doi: 10.1093/cid/ciaa1239.
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Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study.
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Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis.COVID-19 患者的细菌合并感染和继发感染：一项实时快速综述和荟萃分析。
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Use of Procalcitonin and a Respiratory Polymerase Chain Reaction Panel to Reduce Antibiotic Use via an Electronic Medical Record Alert.降钙素原和呼吸聚合酶链反应联合检测在电子病历预警下减少抗生素使用的临床研究
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