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慢性硬膜下血肿的手术清除:再次手术及功能预后的预测因素

Surgical evacuation for chronic subdural hematoma: Predictors of reoperation and functional outcomes.

作者信息

Sioutas Georgios S, Sweid Ahmad, Chen Ching-Jen, Becerril-Gaitan Andrea, Al Saiegh Fadi, El Naamani Kareem, Abbas Rawad, Amllay Abdelaziz, Birkenstock Lyena, Cain Rachel E, Ruiz Ramon L, Buxbaum Michael, Nauheim David O, Renslo Bryan, Bassig Jonathan, Gooch M Reid, Herial Nabeel A, Jabbour Pascal, Rosenwasser Robert H, Tjoumakaris Stavropoula I

机构信息

Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Department of Neurosurgery, The University of Texas Health Science Center, Houston, TX, USA.

出版信息

World Neurosurg X. 2023 Nov 8;21:100246. doi: 10.1016/j.wnsx.2023.100246. eCollection 2024 Jan.

Abstract

BACKGROUND

Although chronic subdural hematoma (CSDH) incidence has increased, there is limited evidence to guide patient management after surgical evacuation.

OBJECTIVE

To identify predictors of reoperation and functional outcome after CSDH surgical evacuation.

METHODS

We identified all patients with CSDH between 2010 and 2018. Clinical and radiographic variables were collected from the medical records. Outcomes included reoperation within 90 days and poor (3-6) modified Rankin Scale score at 3 months.

RESULTS

We identified 461 surgically treated CSDH cases (396 patients). The mean age was 70.1 years, 29.7 % were females, 298 (64.6 %) underwent burr hole evacuation, 152 (33.0 %) craniotomy, and 11 (2.4 %) craniectomy. Reoperation rate within 90 days was 12.6 %, whereas 24.2 % of cases had a poor functional status at 3 months. Only female sex was associated with reoperation within 90 days (OR = 2.09, 95 % CI: 1.17-3.75,  = 0.013). AMS on admission (OR = 5.19, 95 % CI: 2.15-12.52,  < 0.001) and female sex (OR = 3.90, 95 % CI: 1.57-9.70,  = 0.003) were independent predictors of poor functional outcome at 3 months.

CONCLUSION

Careful management of patients with the above predictive factors may reduce CSDH reoperation and improve long-term functional outcomes. However, larger randomized studies are necessary to assess long-term prognosis after surgical evacuation.

摘要

背景

尽管慢性硬膜下血肿(CSDH)的发病率有所上升,但指导手术清除术后患者管理的证据有限。

目的

确定CSDH手术清除术后再次手术和功能结局的预测因素。

方法

我们确定了2010年至2018年间所有CSDH患者。从病历中收集临床和影像学变量。结局包括90天内再次手术以及3个月时改良Rankin量表评分为差(3 - 6分)。

结果

我们确定了461例接受手术治疗的CSDH病例(396例患者)。平均年龄为70.1岁,29.7%为女性,298例(64.6%)接受钻孔引流,152例(33.0%)接受开颅手术,11例(2.4%)接受颅骨切除术。90天内再次手术率为12.6%,而24.2%的病例在3个月时功能状态较差。仅女性性别与90天内再次手术相关(OR = 2.09,95%CI:1.17 - 3.75,P = 0.013)。入院时意识模糊(OR = 5.19,95%CI:2.15 - 12.52,P < 0.001)和女性性别(OR = 3.90,95%CI:1.57 - 9.70,P = 0.003)是3个月时功能结局差的独立预测因素。

结论

对具有上述预测因素的患者进行仔细管理可能会减少CSDH再次手术并改善长期功能结局。然而,需要更大规模的随机研究来评估手术清除术后的长期预后。

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Subdural Hematoma: Predictors of Outcome and a Score to Guide Surgical Decision-Making.硬膜下血肿:预后预测因素和指导手术决策的评分。
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