Bliwise D L, Feldman D E, Bliwise N G, Carskadon M A, Kraemer H C, North C S, Petta D E, Seidel W F, Dement W C
J Am Geriatr Soc. 1987 Feb;35(2):132-41. doi: 10.1111/j.1532-5415.1987.tb01342.x.
This cross-sectional, multivariate study investigated associations between sleep disordered breathing (SDB) and putative risk factors in a heterogeneous group of 720 individuals over the age of 50 years studied during all-night in-lab polysomnography. Results indicated that: aged men were more likely to show impaired respiration during sleep than aged women; excessive daytime somnolence and parasomniac symptoms (snoring, gasping during sleep) were associated with SDB but insomnia was not; obesity accounted for more variance in SDB than age per se, implying that the prevalence of SDB in some elderly persons could be related to the deposition of body fat seen as individuals grow older. All four risk factors (age, sex, obesity, and symptomatic status) were statistically significant and independent predictors of impaired respiration in sleep in the elderly.
这项横断面多变量研究,在720名50岁以上的异质人群中进行了整夜实验室多导睡眠监测,调查了睡眠呼吸障碍(SDB)与假定风险因素之间的关联。结果表明:老年男性比老年女性在睡眠期间更易出现呼吸受损;日间过度嗜睡和异态睡眠症状(打鼾、睡眠中喘气)与SDB相关,但失眠与之无关;肥胖在SDB中所占的变异比年龄本身更大,这意味着一些老年人中SDB的患病率可能与个体随着年龄增长而出现的体脂沉积有关。所有四个风险因素(年龄、性别、肥胖和症状状态)在统计学上都是老年人睡眠呼吸受损的显著且独立预测因素。