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传染性软疣调查 - 荷兰普通实践中治疗和研究的常见方法和态度。

Molluscum contagiosum survey - common approach and attitude towards treatment and research in Dutch general practice.

机构信息

Department of Public Health and Primary Care, Leiden University Medical Center (LUMC), Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.

Department of Dermatology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

出版信息

BMC Prim Care. 2023 Dec 7;24(1):264. doi: 10.1186/s12875-023-02226-y.

Abstract

BACKGROUND

Molluscum contagiosum (MC) can cause significant burden in children. So far, pharmacological treatment has not been proven beneficial. More rigorous interventions have not been well studied. Current guidelines advise a "wait and see" policy. However, children and their parents frequently visit their GP requesting intervention. Therefore, the aim of this study was to gain insight into the approach to MC by GPs and parents' expectations and to investigate willingness to participate in an interventional study.

METHODS

A survey study was carried out among GPs and parents using a questionnaire for each group inquiring about MC and potential study participation. Descriptive statistics were used to analyze results and logistical regression to investigate factors influencing participation.

RESULTS

The majority of GPs (88%) preferred an expectative approach; only 21% were willing to participate in a trial as proposed. GPs estimating ≥ 50% of parents would request treatment, were more likely to participate. Most responding parents did or would visit their GP requesting treatment. In contrast to GPs, 58% were willing to participate. Parents preferring cryotherapy or curettage were more likely to participate.

CONCLUSION

Our study demonstrated that the majority of GPs preferred a conservative approach, adhering to current guidelines. However, most parents preferred treatment to resolve MC and symptoms. Parents' willingness to participate was much higher than GP's, reflecting parents' desire for treatment. These findings underscore the need for continued therapeutic research. Careful preparation and selection of GPs and patients will be essential to ensure the feasibility of such an endeavor.

TRIAL REGISTRATION

This survey study was not part of a clinical trial.

摘要

背景

传染性软疣(MC)可给儿童造成严重负担。迄今为止,药物治疗的益处尚未得到证实。更严格的干预措施尚未得到充分研究。当前的指南建议采取“观望”政策。然而,儿童及其父母经常到他们的全科医生处要求干预。因此,本研究旨在了解全科医生对 MC 的处理方法、父母的期望,并调查他们参与干预性研究的意愿。

方法

使用针对每个群体的问卷对全科医生和父母进行了一项调查研究,询问 MC 和潜在的研究参与情况。使用描述性统计数据来分析结果,并使用逻辑回归来调查影响参与的因素。

结果

大多数全科医生(88%)倾向于采用期待治疗的方法;只有 21%愿意按照提议参加试验。预计会有≥50%的父母要求治疗的全科医生更有可能参与。大多数回应的父母已经或将会去看全科医生要求治疗。与全科医生相比,有 58%的父母愿意参与。选择冷冻疗法或刮除术的父母更有可能参与。

结论

我们的研究表明,大多数全科医生倾向于采取保守的方法,遵循当前的指南。然而,大多数父母更希望通过治疗来解决 MC 和症状。父母参与的意愿远高于全科医生,反映了他们对治疗的渴望。这些发现强调了继续进行治疗研究的必要性。仔细准备和选择全科医生和患者将是确保此类努力可行性的关键。

试验注册

本调查研究不属于临床试验。

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