Bonfá-Araujo Bruno, Blair Mervin, Elnazali Mariam, Tolledo Joy Kirsten, Schermer Julie Aitken, Morrow Sarah A
Department of Psychology, Western University, London, ON, Canada.
Lawson Health Research Institute, London, ON, Canada; Research & Academics Department, Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada.
Mult Scler Relat Disord. 2024 Jan;81:105138. doi: 10.1016/j.msard.2023.105138. Epub 2023 Nov 23.
Comprehending the influence of personality traits on functional outcomes in persons with Multiple Sclerosis (pwMS) can aid in tailoring interventions and support strategies. We explored how demographic variables and personality traits predicted current vocation, information processing speed, anxiety and depression symptoms, and disability level in pwMS.
We used a retrospective chart review on pwMS treated at the London (ON) MS Clinic, that assessed demographic data and personality traits. Participants were 384 (68.8 % females, mean age of 37.8, SD = 10.4) individuals with relapsing and primary progressive MS. We performed hierarchical linear regressions to predict outcomes while considering demographic variables and personality traits.
Younger age, higher education, and conscientiousness were significant predictors for better information processing speed, current vocation, depression symptoms, and disability level. Neuroticism was positively associated with anxiety and depression symptoms, while extraversion was negatively associated with depression symptoms. Women showed higher anxiety symptoms, while men showed higher depression symptoms.
Personality traits, such as neuroticism and conscientiousness, influence psychological outcomes in pwMS. Younger age and higher education are associated with better functional outcomes. Thus, when considering personality traits, future interventions should focus on those with higher neuroticism and lower scores on both extraversion and conscientiousness. Consideration of social support, coping strategies, and disease severity in future research may further enrich our understanding of MS outcomes.
了解人格特质对多发性硬化症患者（pwMS）功能结局的影响有助于制定针对性的干预措施和支持策略。我们探讨了人口统计学变量和人格特质如何预测pwMS患者当前的职业、信息处理速度、焦虑和抑郁症状以及残疾水平。
我们对在安大略省伦敦市MS诊所接受治疗的pwMS患者进行了回顾性病历审查，评估了人口统计学数据和人格特质。参与者为384名复发型和原发性进展型MS患者（68.8%为女性，平均年龄37.8岁，标准差=10.4）。我们进行了分层线性回归，在考虑人口统计学变量和人格特质的同时预测结局。
年龄较小、教育程度较高和尽责性是信息处理速度更快、当前职业状况更好、抑郁症状更少和残疾水平更低的显著预测因素。神经质与焦虑和抑郁症状呈正相关，而外向性与抑郁症状呈负相关。女性焦虑症状较高，而男性抑郁症状较高。
神经质和尽责性等人格特质会影响pwMS患者的心理结局。年龄较小和教育程度较高与更好的功能结局相关。因此，在考虑人格特质时，未来的干预措施应侧重于神经质较高、外向性和尽责性得分较低的人群。在未来研究中考虑社会支持、应对策略和疾病严重程度可能会进一步丰富我们对MS结局的理解。
